Clinical Trial

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

Recruiting Phase 3
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Summary
This phase III trial compares the effect of open thoracic surgery (thoracotomy) to thoracoscopic surgery (video-assisted thoracoscopic surgery or VATS) in treating patients with osteosarcoma that has spread to the lung (pulmonary metastases). Open thoracic surgery is a type of surgery done through a single larger incision (like a large cut) that goes between the ribs, opens up the chest, and removes the cancer. Thoracoscopy is a type of chest surgery where the doctor makes several small incisions and uses a small camera to help with removing the cancer. This trial is being done evaluate the two different surgery methods for patients with osteosarcoma that has spread to the lung to find out which is better.
Protocol Amendment History 39 amendments
This ClinicalTrials.gov record has been amended 39 times since 2022-01-31; most recent amendment 2026-05-01.
Status change: Not Yet Recruiting → Recruiting 2022-02-25
Trial Details
NCT Number NCT05235165
Lead Sponsor Children's Oncology Group
Collaborators: National Cancer Institute (NCI)
Conditions Metastatic Malignant Neoplasm in the Lung, Metastatic Osteosarcoma, Osteosarcoma
Enrollment 62 participants
Start Date 2022-04-01
Primary Completion 2031-03-31 (estimated)
Study Completion 2031-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-05-05