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Study of Sacituzumab Govitecan Combinations in First-line Treatment of Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC)

Study acronym: EVOKE-02
StatusActive, Not Recruiting
PhasePhase 2
Started2022-05-30
View on ClinicalTrials.gov ↗
The goal of this clinical study is to learn more about the study drug, sacituzumab govitecan-hziy (SG), and its dosing in combination with pembrolizumab or pembrolizumab and a platinum agent (carboplatin or cisplatin), in participants with advanced or metastatic (cancer that has spread) non-small-cell lung cancer (NSCLC).

Amendment history 2 changes detected by DataLookout

2026-09-12
notable
Primary completion pushed: 2026-09 → 2027-03
2026-09-12
minor
Completion pushed: 2026-09 → 2027-03
Trial Details
NCT Number NCT05186974
Lead Sponsor Gilead Sciences
Collaborators: Merck Sharp & Dohme LLC
Conditions Non-small Cell Lung Cancer
Enrollment 193 participants
Start Date 2022-05-30
Primary Completion 2027-03 (estimated)
Study Completion 2027-03 (estimated)
Updated on ClinicalTrials.gov 2026-09-11