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Repurposing Low-Dose Clonidine for PTSD in Veterans

StatusRecruiting
PhasePhase 3
Started
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Record History

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  1. Primary and study completion dates: Mar 31, 2026 to Mar 31, 2027v14
  2. Primary and study completion dates: Mar 2026 to Mar 31, 2026v13
  3. Primary completion date: Mar 31, 2025 to Mar 2026
    • Study completion date: Nov 2025 to Mar 2026
    v12
  4. Re-verified, no change to tracked fieldsv11
  5. Primary completion date: Jul 2024 to Mar 31, 2025
    • Study completion date: Nov 2024 to Nov 2025
    v10
Show 8 earlier versionsHide 8 earlier versions
  1. Re-verified, no change to tracked fieldsv9
  2. Primary completion date: Dec 2023 to Jul 2024
    • Study completion date: Sep 2024 to Nov 2024
    v8
  3. Trial status: Not Yet Recruiting to Recruiting
    • Start date changed from estimate of Apr 2023 to Jun 1, 2023
    • Site details revised
    v7
  4. Start date: Feb 2023 to Apr 2023v6
  5. Primary endpoints: 5 to 3
    • Eligibility criteria expanded, about 151 words
    • Secondary endpoints: 9 to 3
    • Site contact updated
    v5
  6. Start date: Sep 2022 to Feb 2023v4
  7. Primary completion date: Jul 2022 to Dec 2023
    • Start date: May 2022 to Sep 2022
    • Study completion date: Aug 2022 to Sep 2024
    v3
  8. Start date: Jul 2021 to May 2022v2
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Hypothesis: Veterans with PTSD prescribed clonidine will demonstrate improvements in PTSD symptoms, including daytime, nighttime, and sleep-related behaviors.
Trial Details
NCT Number NCT04877093
Lead Sponsor Wake Forest University Health Sciences
Conditions
(from sponsor)		 PTSD, Posttraumatic Stress Disorder, Sleep
Related terms Stress Disorders, Post-Traumatic
Enrollment 32 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov