GDM and Its Consequences in Mothers and Offsprings

Gestational diabetes mellitus (GDM) is one of the most common disorders which occured during pregnancy. GDM is not only associated with short-term maternal and fetal adverse outcomes, but also related to a wide range of long-term consequences for both mother and child. The GDM and Its Consequences for mothers and offsprings (GDMCMO) aims to establish a cohort to follow both maternal and offsprings'short-term and long-term outcomes, including fetal malformations including congenital heart diseases, birth weight, preterm birth, caesarean section delivery, body growth and neurodevelopment after birth, obesity, type 2 diabetes and impaired insulin sensitivity and secretion, lung health and allergic diseases later in life for offspring, as well as future type 2 diabetes and cardiovascular risk factors for mother after delivery. Biological samples including blood and tissue samples of mothers and children are also collected during pregnancy and after delivery.

NCT Number	NCT04529889
Lead Sponsor	Guangzhou Women and Children's Medical Center
Conditions	Gestational Diabetes Mellitus, Pregnancy Outcome, Neurodevelopment, Immune Development, Childhood Obesity, Host and Microbiome
Enrollment	7,000 participants
Start Date	2012-02-01
Primary Completion	2038-12-31 (estimated)
Study Completion	2038-12-31 (estimated)
Updated on ClinicalTrials.gov	2023-09-13