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The RIPPLE AT-PLUS Study

StatusActive, Not Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated September 25, 2025 (before its estimated April 2026 completion). Its status may not reflect the trial's current state.

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary completion date: Aug 2024 to Apr 2026v6 Show 6 more changesShow less
    • Trial status: Not Yet Recruiting to Active, Not Recruiting
    • Enrollment target: estimated 200 to confirmed 201
    • Study completion date: Aug 2025 to Apr 2026
    • Start date changed from estimate of Aug 23, 2022 to Aug 16, 2022
    • Site contacts updated at 3 of 3 sites
    • Collaborators: 2 to 7
  2. Lead sponsor: Imperial College London to Liverpool Heart and Chest Hospital NHS Foundation Trustv5 Show 9 more changesShow less
    • Primary completion date: Apr 2021 to Aug 2024
    • Start date: Jun 23, 2020 to Aug 23, 2022
    • Trial status: Recruiting to Not Yet Recruiting
    • Study sites: 2 to 3
    • Study completion date: Apr 2022 to Aug 2025
    • Eligibility criteria shortened, about 71 words
    • Secondary endpoints revised (5)
    • Study description expanded, about 11 words
    • Collaborators revised (2)
  3. Trial status: Not Yet Recruiting to Recruiting
    • Study sites: 3 to 2
    • Start date changed from estimate of Apr 2020 to Jun 23, 2020
    v4
  4. Start date: Sep 2019 to Apr 2020
    • Primary completion date: Sep 2021 to Apr 2021
    • Study completion date: Sep 2022 to Apr 2022
    v3
  5. Start date: May 2019 to Sep 2019v2 Show 4 more changesShow less
    • Primary completion date: May 2021 to Sep 2021
    • Study completion date: May 2021 to Sep 2022
    • Study description shortened, about 299 words
    • Study title shortened, about 3 words
  6. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Atrial tachycardia is a symptomatic arrhythmia, for which an effective treatment is a catheter ablation procedure. The goal of the Ripple AT-Plus study is to evaluate two methods of performing catheter ablation for atrial tachycardia. The main outcome assessed during the study is long-term recurrence of atrial tachycardia following the catheter ablation procedure.
Trial Details
NCT Number NCT03915691
Lead Sponsor Liverpool Heart and Chest Hospital NHS Foundation Trust
Collaborators: Imperial College Healthcare NHS Trust, Norfolk & Norwich University Hospital Trust, Nottingham University Hospitals NHS Trust, University Hospital Plymouth NHS Trust, Blackpool Teaching Hospitals NHS Trust, Cardiff & Vale UHB, University Hospitals Sussex NHS Foundation Trust
Conditions
(from sponsor)		 Atrial Tachycardia
Related terms Atrial Fibrillation
Enrollment 201 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov