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China Rural Hypertension Control Project

Study acronym: CRHC
StatusActive, Not Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated December 18, 2025 (before its estimated January 2026 completion). Its status may not reflect the trial's current state.

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary endpoints: 5 to 4
    • Secondary endpoints: 26 to 27
    v11
  2. Primary completion date: Mar 26, 2023 to Jan 2026v10 Show 4 more changesShow less
    • Primary endpoints: 3 to 5
    • Study completion date: Jun 30, 2024 to Dec 2026
    • Secondary endpoints: 16 to 26
    • Study description expanded, about 38 words
  3. Primary endpoints revised (3)
    • Primary completion date changed from estimate of Jun 30, 2023 to Mar 26, 2023
    • Secondary endpoints: 17 to 16
    • Study description shortened, about 1 word
    v9
  4. Secondary endpoints revised (17)v8
  5. Secondary endpoints: 16 to 17v7
Show 5 earlier versionsHide 5 earlier versions
  1. Primary endpoints: 2 to 3
    • Secondary endpoints: 11 to 16
    • Study description expanded, about 14 words
    v6
  2. Primary completion date: Dec 31, 2021 to Jun 30, 2023v5 Show 5 more changesShow less
    • Study completion date: Dec 31, 2022 to Jun 30, 2024
    • Interventions: Enhancing the awareness of blood pressure self-management (Behavioral), Enhancing village doctors'ability. (Other), Establishing a chronic… to Village-doctor-led multifaceted intervention (Other)
    • Eligibility criteria expanded, about 44 words
    • Study description shortened, about 13 words
    • Collaborators: 5 to 8
  3. Trial status: Recruiting to Active, Not Recruitingv4 Show 4 more changesShow less
    • Enrollment target: 36520 to 33995
    • Secondary endpoints revised (11)
    • Study site revised
    • Study description shortened, about 5 words
  4. Trial status: Not Yet Recruiting to Recruitingv3 Show 4 more changesShow less
    • Primary completion date: Dec 2021 to Dec 31, 2021
    • Study completion date: Dec 2022 to Dec 31, 2022
    • Start date changed from estimate of May 2018 to May 8, 2018
    • Site details revised
  5. Secondary endpoints: details revised at 1 of 11 entriesv2
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
China Rural Hypertension Control (CRHC) Project is a cluster randomized trial that will test the effectiveness of a village doctor-led multifaceted intensive blood pressure intervention on hypertension control in 18 months (Phase 1), cardiovascular disease risk in 36 months (Phase 2), and all-cause dementia in 48 months (Phase 3) among patients with hypertension in rural China. An extended observational follow-up, the CRHCP post-intervention observational follow-up study, will be conducted at Year 7 to evaluate long-term effects.
Trial Details
NCT Number NCT03527719
Lead Sponsor First Hospital of China Medical University
Collaborators: Tulane University, First Affiliated Hospital Xi'an Jiaotong University, Tongji Hospital, Disease Control and Prevention Centre of Liaoning Province, Chaoyang Central Hospital, Hanzhong People's Hospital, Disease Control and Prevention Centre of Chaoyang City, Shengjing Hospital
Conditions
(from sponsor)		 Hypertension
Related terms Cardiovascular Diseases, Dementia, Hypertension, Stroke
Enrollment 33,995 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov