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Pathophysiology and Risk of Atrial Fibrillation Detected After Ischemic Stroke

Study acronym: PARADISE
StatusCompleted
PhaseNot specified
Started2017-04-18
View on ClinicalTrials.gov ↗

Amendment history

2026-09-19
Trial completed
Final enrollment: 45 participants (planned 100)
Primary completion confirmed: April 2019 (last estimated May 2026)
2025-03-27
Study Status, Oversight v5
Primary completion date2024-05-07→2026-05-07
Completion date2025-05-07→2026-05-07
2023-10-04
Study Status, Sponsor/Collaborators v4
Primary completion date2023-05-07→2024-05-07
Completion date2023-05-07→2025-05-07
Collaborators6 to 5 entries
University of Western Ontario, Canada
2022-05-10
Study Status v3
Primary completion date2020-03-30→2023-05-07
Completion date2020-03-30→2023-05-07
2020-02-27
Study Status v2
Primary completion date2019-03-30→2020-03-30
Completion date2019-04-30→2020-03-30
2018-11-16
Recruiting→Active, Not Recruiting Study Status, Contacts/Locations v1
Trial statusRecruiting→Active, Not Recruiting
Primary completion date2018-08-31→2019-03-30
Study sitesdetails revised at 1 of 1 site
2017-09-05
Original filing
This prospective non-interventional cohort study investigates the pathophysiology of Atrial Fibrillation Detected After Stroke or transient ischemic attack (AFDAS) by comparing the autonomic function and inflammation between patients with AFDAS, patients with atrial fibrillation (AF) diagnosed before the ischemic event or known AF (KAF), and patients with normal sinus rhythm (NSR) after 14 day of cardiac monitoring following the event onset.
Trial Details
NCT Number NCT03275155
Lead Sponsor London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Collaborators: Western University, Canada, London Health Sciences Centre, Parkwood Hospital, London, Ontario, El Instituto de Neurociencia Cognitiva y Traslacional (INCYT), Instituto de Neurologia Cognitiva (INECO)
Conditions Stroke, Ischemic, Transient Ischemic Attack, Atrial Fibrillation
Enrollment 45 participants
Start Date 2017-04-18
Primary Completion 2019-04-29 (estimated)
Study Completion 2020-03-26 (estimated)
Updated on ClinicalTrials.gov 2026-09-18