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Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

StatusActive, Not Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

The 50 most recent of 1375 record versions are accounted for below. See every version on ClinicalTrials.gov ↗

  1. Study sites revised (1660)
  2. Final enrollment: 7458 participants (planned 8300) Primary completion date changed from estimate of Sep 28, 2026 to Dec 3, 2025 · Completion pushed from Sep 28, 2026 to Sep 21, 2027 · Site details revised at 135 of 1660 sites Show 3 more changesShow less
    • Primary completion date changed from estimate of Sep 28, 2026 to Dec 3, 2025
    • Completion pushed from Sep 28, 2026 to Sep 21, 2027
    • Site details revised at 135 of 1660 sites
  3. Study sites revised (1660)v1373 See this version in full on ClinicalTrials.gov ↗
  4. Re-verified, no change to tracked fieldsv1372
  5. Study sites: 1661 to 1660v1371
Show 45 earlier versionsHide 45 earlier versions
  1. Study sites revised (1661)v1370 See this version in full on ClinicalTrials.gov ↗
  2. Study sites revised (1661)v1369 See this version in full on ClinicalTrials.gov ↗
  3. Study sites revised (1661)v1368 See this version in full on ClinicalTrials.gov ↗
  4. Study sites revised (1661)v1367 See this version in full on ClinicalTrials.gov ↗
  5. Study sites revised (1661)v1366 See this version in full on ClinicalTrials.gov ↗
  6. Study sites revised (1661)v1365 See this version in full on ClinicalTrials.gov ↗
  7. Study sites revised (1661)v1364 See this version in full on ClinicalTrials.gov ↗
  8. Study sites: 1662 to 1661v1363
  9. Study sites revised (1662)v1362 See this version in full on ClinicalTrials.gov ↗
  10. Re-verified, no change to tracked fieldsv1361
  11. Study sites revised (1662)v1360 See this version in full on ClinicalTrials.gov ↗
  12. Study sites: 1663 to 1662v1359
  13. Study sites revised (1663)v1358 See this version in full on ClinicalTrials.gov ↗
  14. Study sites revised (1663)v1357 See this version in full on ClinicalTrials.gov ↗
  15. 8 versions Re-verified since Mar 31, 2026, no change to tracked fieldsv1349-v1356
  16. Study sites revised (1663)v1348 See this version in full on ClinicalTrials.gov ↗
  17. 10 versions Re-verified since Mar 14, 2026, no change to tracked fieldsv1338-v1347
  18. Study Status, Contacts/Locationsv1337
  19. 11 versions Re-verified since Feb 26, 2026, no change to tracked fieldsv1326-v1336
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.
Trial Details
NCT Number NCT02194738
Lead Sponsor National Cancer Institute (NCI)
Conditions Stage IB Lung Non-Small Cell Carcinoma AJCC v7, Stage II Lung Non-Small Cell Cancer AJCC v7, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIA Lung Non-Small Cell Cancer AJCC v7, Stage IIIB Lung Cancer AJCC v8
Enrollment 7,458 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov