The Hurria Older PatiEnts (HOPE) With Breast Cancer Study

StatusActive, Not Recruiting
PhaseNot specified
Started

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Record History

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  1. Study completion pushed from Sep 18, 2026 to Sep 8, 2027
    • Eligibility criteria expanded, about 16 words
    • Publications: details revised at 4 of 4 entries
  2. Study completion date: Oct 9, 2025 to Sep 18, 2026v26
  3. Study completion date: Dec 30, 2024 to Oct 9, 2025v25
  4. Study completion date: Dec 30, 2023 to Dec 30, 2024v24
  5. Study completion date: Apr 30, 2023 to Dec 30, 2023v23
Show 21 earlier versionsHide 21 earlier versions
  1. Study title shortened, about 1 wordv22
  2. Primary completion date changed from estimate of Apr 30, 2022 to Dec 2, 2018
    • Study completion date: Apr 30, 2022 to Apr 30, 2023
    v21
  3. Primary and study completion dates: Apr 2022 to Apr 30, 2022v20
  4. Primary and study completion dates: Apr 2020 to Apr 2022v19
  5. Re-verified, no change to tracked fieldsv18
  6. Primary and study completion dates: Apr 2019 to Apr 2020v17
  7. Primary and study completion dates: Apr 2018 to Apr 2019
    • Trial status: Recruiting to Active, Not Recruiting
    • Site details revised at 17 of 17 sites
    v16
  8. Primary completion date: Apr 2017 to Apr 2018
    • Study completion date: Apr 2018
    • Start date: Sep 2011 to Sep 9, 2011
    v15
  9. Primary completion date: Sep 2016 to Apr 2017v14
  10. Study sites: 15 to 17v13
  11. 2 versions Re-verified since Feb 26, 2015, no change to tracked fieldsv11-v12
  12. Study sites: 10 to 15v10
  13. Study sites: 9 to 10v9
  14. 2 versions Re-verified since Nov 13, 2013, no change to tracked fieldsv7-v8
  15. Study sites: 8 to 9v6
  16. Primary endpoints: 3 to 4
    • Eligibility criteria expanded, about 82 words
    v5
  17. Enrollment target: 500 to 700v4
  18. Re-verified, no change to tracked fieldsv3
  19. Study sites: 7 to 8v2
  1. Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this study is to develop a "bedside to bench" model of clinical and biological predictors for toxicity to adjuvant and neoadjuvant chemotherapy in older adults with breast cancer. The investigators will develop a predictive model using clinical and biological predictors of toxicity to adjuvant and neoadjuvant chemotherapy in older adults with breast cancer. The investigators will also determine the association between clinical and biological factors and reduced relative dose intensity of the prescribed chemotherapy regimen. In addition, the investigators will explore specific chemotherapy toxicities associated with reduced relative dose intensity of a prescribed regimen.
Trial Details
NCT Number NCT01472094
Lead Sponsor City of Hope Medical Center
Collaborators: National Institutes of Health (NIH), National Institute on Aging (NIA)
Conditions
(from sponsor)		 Breast Cancer
Related terms Breast Neoplasms
Enrollment 700 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov