Sponsor Pipeline

National Eye Institute (NEI) Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
21
Active Trials
17
Recruiting
10
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-11 NCT04458935
Retrospective Case Series of Trans-scleral Cryotherapy for Retinal Hemangioblastoma
Trial completed
2026-06-11 NCT01352975
Study of Dark Adaptation in Age-Related Macular Degeneration
Trial completed
2026-06-11 NCT03225131
Dark Adaptation in Participants With Age-Related Macular Degeneration
Trial completed
2026-06-11 NCT03225131
Dark Adaptation in Participants With Age-Related Macular Degeneration
date change Primary completion moved earlier: 2033-12-31 -> 2025-08-15
2026-06-11 NCT03225131
Dark Adaptation in Participants With Age-Related Macular Degeneration
date change Completion moved earlier: 2033-12-31 -> 2025-08-15
2026-06-05 NCT04545736
Oral Metformin for Treatment of ABCA4 Retinopathy
overall status: "Recruiting" → "Active Not Recruiting"
2026-06-05 NCT04545736
Oral Metformin for Treatment of ABCA4 Retinopathy
date change Primary completion moved earlier: 2028-09-30 -> 2028-02-02
2026-06-05 NCT04545736
Oral Metformin for Treatment of ABCA4 Retinopathy
date change Completion pushed: 2028-09-30 -> 2029-02-02
2026-06-05 NCT02771236
Clinical and Molecular Studies in Families With Inherited Eye Disease
Enrollment reduced: 5800 -> 5000 participants
2026-06-03 NCT02771236
Clinical and Molecular Studies in Families With Inherited Eye Disease
Enrollment increased: 5000 -> 5800 participants
Active Trials by Phase
Phase 1/2
2
Phase 1
1
Not specified
18
Active Trials
NCT IDTitleConditionStatus
Phase 1/2
NCT04339764 Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment… Dry Age-Related Macular Degeneration Recruiting
NCT04545736 Oral Metformin for Treatment of ABCA4 Retinopathy ABCA4 Retinopathy Active, Not Recruiting
Phase 1
NCT04289571 Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease Cone-Rod Degeneration Recruiting
Not specified
NCT01778543 Pathogenesis and Genetics of Microphthalmia, Anophthalmia and Uveal Coloboma (MAC) Coloboma Recruiting
NCT02317328 Adaptive Optics Retinal Imaging Eye Diseases Recruiting
NCT02077894 Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye… Genetic Eye Disease Recruiting
NCT02617966 Rod and Cone Mediated Function in Retinal Disease Retinal Degeneration Recruiting
NCT02821767 Natural History, Pathogenesis, and Outcome of Ocular Disorders Eye Disease Recruiting
NCT01145196 Genotype-Phenotype Study of Patients With Plaquenil -Induced Retinal Toxicity, With… Genotype Recruiting
NCT01432847 Cell Collection to Study Eye Diseases Retinal Disease Recruiting
NCT01496625 National Eye Institute Biorepository for Retinal Diseases Age-Related Macular Degeneration Recruiting
NCT02471287 Genetics of Inherited Eye Disease Genetic Eye Disease Recruiting
NCT02741440 Natural History of Spinocerebellar Ataxia Type 7 (SCA7) Spinocerebellar Ataxia Recruiting
NCT02771236 Clinical and Molecular Studies in Families With Inherited Eye Disease Inherited Eye Disease Recruiting
NCT03407066 Perception, Sensation, Cognition and Action in Humans Normal Physiology Recruiting
NCT04591483 Stargardt-like Macular Dystrophy (STDG3) Secondary to Mutations in ELOVL4 Stargardt-Like Macular Dystrophy Recruiting
NCT00655096 Screening for Research Participants Eye Diseases Recruiting
NCT06491615 National Ophthalmic Genotyping and Phenotyping Network (eyeGENE (Registered Trademark))… Inherited Ophthalmic Diseases Recruiting
NCT01736293 Natural History of Eye Diseases Related to ABCA4 Mutations Retinal Degeneration Active, Not Recruiting
NCT00594672 Age-Related Eye Disease Study (AREDS) Follow-Up Age-Related Macular Degeneration Active, Not Recruiting
NCT00055029 Clinical and Genetic Studies of X-Linked Juvenile Retinoschisis Retinoschisis Active, Not Recruiting
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