This study is a 5-year extension of the AREDS protocol, in which investigators followed the natural course of age-related macular degeneration (AMD) and cataracts. Participants in the former AREDS protocol are eligible for this study.
Participants have a complete eye examination once a year and are contacted at least once a year between visits to check on their status. The eye examination includes measurement of visual acuity (vision chart test) and examination of the inside of the eye after the pupils have been dilated with eye drops. Photographs of the inside of the eye may be taken using a special camera that flashes a bright light in the eye. A blood sample may be obtained to test for cholesterol level and genes related to inflammation.
Protocol Amendment History
369 amendments
This ClinicalTrials.gov record has been amended 369 times since 2008-01-04; most recent amendment 2026-07-16.
Status change: Enrolling by Invitation → Active, Not Recruiting2018-11-21
Status change: Recruiting → Enrolling by Invitation2015-11-17