| Detected | Trial | Change |
|---|---|---|
| 2026-06-02 | NCT06078553 A Natural History Study in Participants With Congenital Myasthenic Syndromes (CMS) Due to… |
Trial sites expanded: 23 -> 30 locations |
| 2026-06-02 | NCT07284420 ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to… |
Trial sites expanded: 10 -> 13 locations |
| 2026-06-02 | NCT07294170 ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy… |
Trial sites expanded: 10 -> 15 locations |
| 2026-05-29 | NCT07091630 A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP |
Trial sites expanded: 43 -> 56 locations |
| 2026-05-28 | NCT06078553 A Natural History Study in Participants With Congenital Myasthenic Syndromes (CMS) Due to… |
Trial sites expanded: 20 -> 23 locations |
| 2026-05-21 | NCT06742190 A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With… |
overall status: "Recruiting" → "Active Not Recruiting" |
| 2026-05-21 | NCT06742190 A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With… |
Primary endpoint(s) modified |
| 2026-05-21 | NCT06742190 A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With… |
Enrollment increased: 115 -> 154 participants |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-06-10 | NCT07638566 A Study to Assess the Correct Dose, Safety and Efficacy of Empasiprubart in Adolescent… | Phase 2/3 | Not Yet Recruiting |
| 2026-05-28 | NCT07610564 A Study to Assess the Effect of Empasiprubart on Nerve Morphology by Ultrasound in Adults… | Phase 1 | Not Yet Recruiting |
| 2026-05-28 | NCT07612020 A Study to Assess the Absolute Bioavailability of Empasiprubart SC Administered With an… | Phase 1 | Recruiting |
| 2026-05-19 | NCT07595653 A Study to Evaluate the Impact of Efgartigimod on Overall Disease Experience of People… | Recruiting | |
| 2026-05-19 | NCT07596849 A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants… | Phase 3 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT06909214 | A Study to Evaluate the Clinical Outcomes of Efgartigimod PH20 SC in Adults With… | New Onset Generalized Myasthenia Gravis (gMG) | Recruiting |
| Phase 3 | |||
| NCT06544499 | A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With… | Primary Immune Thrombocytopenia (ITP) | Recruiting |
| NCT06920004 | A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP | Chronic Inflammatory Demyelinating Polyneuropathy | Recruiting |
| NCT07091630 | A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP | Chronic Inflammatory Demyelinating Polyneuropathy | Recruiting |
| NCT04812925 | A Phase 3 Study to Evaluate the Safety and Efficacy of Efgartigimod PH20 Subcutaneous in… | Primary Immune Thrombocytopenia | Active, Not Recruiting |
| NCT06684847 | A Study of the Efficacy and Safety of Efgartigimod in Patients With Primary Sjögren's… | Primary Sjogrens Disease | Active, Not Recruiting |
| NCT07570316 | A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants… | Graves' Disease | Not Yet Recruiting |
| NCT07596849 | A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants… | Graves Disease | Not Yet Recruiting |
| NCT06742190 | A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With… | Multifocal Motor Neuropathy (MMN) | Active, Not Recruiting |
| NCT05979441 | A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of… | Myositis | Enrolling by Invitation |
| Phase 2/3 | |||
| NCT04833894 | Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of Efgartigimod… | Generalized Myasthenia Gravis | Recruiting |
| NCT07194850 | A Study of Efgartigimod IV in Participants From 12 Years to Less Than 18 Years of Age… | Immune Thrombocytopenia (ITP) | Recruiting |
| NCT06392386 | A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age With… | Generalized Myasthenia Gravis | Recruiting |
| NCT05374590 | Evaluating Long-term Safety of Efgartigimod Administered Intravenously and Efgartigimod… | Generalized Myasthenia Gravis | Enrolling by Invitation |
| NCT07638566 | A Study to Assess the Correct Dose, Safety and Efficacy of Empasiprubart in Adolescent… | Chronic Inflammatory Demyelinating Polyradiculoneuropathy | Not Yet Recruiting |
| Phase 2 | |||
| NCT06503731 | A Study to Evaluate the Safety and Tolerability of Efgartigimod PH20 SC Given by… | Antibody-mediated Rejection | Recruiting |
| NCT06655155 | A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic… | Systemic Sclerosis (SSc) | Recruiting |
| NCT07287982 | A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and… | Spinal Muscular Atrophy (SMA) | Recruiting |
| NCT07284420 | ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to… | AChR-Ab Seropositive Generalized Myasthenia Gravis | Recruiting |
| NCT05405361 | A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy… | Multifocal Motor Neuropathy (MMN) | Active, Not Recruiting |
| NCT05907096 | ARGX-117 in Deceased Donor Kidney Transplant Recipients at Risk for Delayed Graft Function | Delayed Graft Function | Active, Not Recruiting |
| NCT06441682 | A Safety and Efficacy Study of ARGX-119 in Adult Patients With Amyotrophic Lateral… | Amyotrophic Lateral Sclerosis | Active, Not Recruiting |
| NCT07583641 | A Study to Learn About How Well the Medicine Efgartigimod Works to Treat Autoimmune… | Autoimmune Encephalitis (AE) | Not Yet Recruiting |
| Phase 1 | |||
| NCT07377396 | A Study to Assess the Safety of ARGX-124 in Healthy Volunteers | Healthy Volunteers | Recruiting |
| NCT06436742 | A Phase 1b Study to Investigate Safety and Tolerability of ARGX-119 in Adult Participants… | Congenital Myasthenic Syndrome | Recruiting |