| Detected | Trial | Change |
|---|---|---|
| 2026-08-12 | NCT06878976 A Study to Assess the Long-term Safety and Efficacy of Solriamfetol in Subjects With… |
Primary endpoint(s) modified |
| 2026-08-12 | NCT06878976 A Study to Assess the Long-term Safety and Efficacy of Solriamfetol in Subjects With… |
Enrollment reduced: 300 -> 236 participants |
| 2026-08-12 | NCT06878976 A Study to Assess the Long-term Safety and Efficacy of Solriamfetol in Subjects With… |
Trial arms changed: 1 -> 2 |
| 2026-08-12 | NCT06878976 A Study to Assess the Long-term Safety and Efficacy of Solriamfetol in Subjects With… |
date change Primary completion pushed: 2026-12 -> 2027-12 |
| 2026-08-12 | NCT06878976 A Study to Assess the Long-term Safety and Efficacy of Solriamfetol in Subjects With… |
date change Completion pushed: 2026-12 -> 2027-12 |
| 2026-07-29 | NCT06413433 Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using… |
date change Primary completion pushed: 2025-12 -> 2026-12 |
| 2026-07-29 | NCT06413433 Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using… |
date change Completion pushed: 2025-12 -> 2026-12 |
| 2026-07-25 | NCT07637162 Open-Label Safety Study of AXS-14 in Subjects With Fibromyalgia |
Trial sites expanded: 8 -> 18 locations |
| 2026-07-25 | NCT07484217 Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness… |
Trial sites expanded: 13 -> 40 locations |
| 2026-07-25 | NCT06568367 Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work… |
Trial sites expanded: 40 -> 49 locations |
| 2026-07-25 | NCT07398417 Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research… |
Trial sites expanded: 16 -> 51 locations |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-08-14 | NCT07766655 A Study to Evaluate the Efficacy and Safety of AXS-05 for Smoking Cessation in Adults | Phase 3 | Recruiting |
| 2026-07-21 | NCT07717879 A Study to Assess the Efficacy and Safety of Solriamfetol in Children With ADHD | Phase 3 | Recruiting |
| 2026-07-21 | NCT07717892 A Study to Assess the Efficacy and Safety of Solriamfetol in Adolescents With ADHD | Phase 3 | Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 4 | |||
| NCT06223880 | A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the… | Major Depressive Disorder | Recruiting |
| Phase 3 | |||
| NCT07717879 | A Study to Assess the Efficacy and Safety of Solriamfetol in Children With ADHD | ADHD | Recruiting |
| NCT07717892 | A Study to Assess the Efficacy and Safety of Solriamfetol in Adolescents With ADHD | ADHD | Recruiting |
| NCT06568367 | Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work… | Excessive Sleepiness | Recruiting |
| NCT07398417 | Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research… | Fibromyalgia | Recruiting |
| NCT07484217 | Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness… | Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms | Recruiting |
| NCT06413433 | Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using… | Binge-Eating Disorder | Recruiting |
| NCT07766655 | A Study to Evaluate the Efficacy and Safety of AXS-05 for Smoking Cessation in Adults | Smoking Cessation | Recruiting |
| NCT07637162 | Open-Label Safety Study of AXS-14 in Subjects With Fibromyalgia | Fibromyalgia | Enrolling by Invitation |
| NCT06878976 | A Study to Assess the Long-term Safety and Efficacy of Solriamfetol in Subjects With… | Binge-Eating Disorder | Enrolling by Invitation |
| Not specified | |||
| NCT06413420 | SUNOSI® (Solriamfetol) Pregnancy Registry | Narcolepsy | Recruiting |