Drug Pipeline

Pacritinib Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
16
Active Studies
12
Recruiting
1
Phase 3
10
Top Sponsors
5
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-27 NCT06516887
Study of Bemcentinib Plus Pacritinib In Patients With Advanced Lung Adenocarcinoma
Trial terminated — check why_stopped for reason
2026-05-27 NCT06516887
Study of Bemcentinib Plus Pacritinib In Patients With Advanced Lung Adenocarcinoma
critical why stopped: null → "Investigational drug limitations"
2026-05-27 NCT06516887
Study of Bemcentinib Plus Pacritinib In Patients With Advanced Lung Adenocarcinoma
Enrollment reduced: 44 -> 4 participants
2026-05-27 NCT06516887
Study of Bemcentinib Plus Pacritinib In Patients With Advanced Lung Adenocarcinoma
date change Primary completion moved earlier: 2027-09-01 -> 2026-05-21
2026-05-27 NCT06516887
Study of Bemcentinib Plus Pacritinib In Patients With Advanced Lung Adenocarcinoma
date change Completion moved earlier: 2027-09-01 -> 2026-05-21
Active Studies by Phase
Phase 3
1
Phase 2
10
Phase 1/2
3
Phase 1
1
Early Phase 1
1
Active Trials
NCT IDTitleConditionStatus
Phase 3
NCT03165734 A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia… Primary Myelofibrosis Active, Not Recruiting
Phase 2
NCT04858256 Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms T-Cell Neoplasm Recruiting
NCT05980806 A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and… Myelofibrosis Recruiting
NCT07148947 Pacritinib With Standard of Care Azacitidine or Decitabine as a Bridge to Allogeneic… Accelerated Phase Myeloproliferative Neoplasm Recruiting
NCT07033598 Pacritinib vs. Hydroxyurea in Advanced Proliferative Chronic Myelomonocytic Leukemia Leukemia, Myelomonocytic, Chronic Recruiting
NCT04282187 Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of… Acute Myeloid Leukemia Recruiting
NCT06782373 A Study to Assess the Effectiveness and Safety of Pacritinib in Patients With VEXAS… VEXAS Recruiting
NCT07394153 Pacritinib For Bone Marrow Fibrosis In Patients With Myelofibrosis Who Have… Myelofibrosis,MF Recruiting
NCT06052618 Phase II Study of Pacritinib in Kaposi Sarcoma Herpesvirus (KSHV)-Associated Multicentric… KSHV Inflammatory Cytokine Syndrome (KICS) Recruiting
NCT07447817 Selinexor and Pacritinib in JAK Inhibitor-naïve MF Patients With Cytopenias Myelofibrosis Not Yet Recruiting
NCT07226713 Pacritinib in Participants With Metastatic Castrate-Resistant Prostate Cancer That… Prostate Cancer Not Yet Recruiting
Phase 1/2
NCT05531786 Phase I/II Study of Pacritinib, A JAK2/IRAK1/CSF1R Inhibitor, in Refractory Chronic… Graft vs Host Disease Recruiting
NCT06303193 Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric… Myelodysplastic Syndromes Recruiting
NCT07387354 Pacritinib With Aza for Upfront Myelodysplastic Syndrome Myelodysplastic Syndromes Not Yet Recruiting
Phase 1
NCT06675123 Pacritinib in Combination With a BTK Inhibitor for the Treatment of Patients With… Recurrent Mantle Cell Lymphoma Recruiting
Early Phase 1
NCT06414681 Combination of Tagraxofusp With Pacritinib in Patients With Intermediate-1 or Higher… Myelofibrosis,MF Recruiting
Sponsors Running Pacritinib Trials
Disease Areas
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