Drug Pipeline

mFOLFOX6 Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
18
Active Studies
8
Recruiting
4
Phase 3
10
Top Sponsors
8
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-11 NCT06835569
A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With…
Enrollment increased: 188 -> 448 participants
2026-06-11 NCT06835569
A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With…
Trial arms changed: 2 -> 10
2026-06-03 NCT06917079
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
Primary endpoint(s) modified
2026-06-03 NCT06917079
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
Enrollment increased: 387 -> 665 participants
2026-06-03 NCT06917079
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
Trial arms changed: 14 -> 20
2026-06-03 NCT06917079
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
Trial sites expanded: 11 -> 17 locations
2026-05-28 NCT05052801
Bemarituzumab or Placebo Plus Chemotherapy in Gastric Cancers With Fibroblast Growth…
Trial completed
2026-05-28 NCT05052801
Bemarituzumab or Placebo Plus Chemotherapy in Gastric Cancers With Fibroblast Growth…
date change Completion moved earlier: 2026-06-20 -> 2026-04-26
Active Studies by Phase
Phase 4
1
Phase 3
3
Phase 2/3
1
Phase 2
6
Phase 1/2
2
Phase 1
3
Not specified
2
Active Trials
NCT IDTitleConditionStatus
Phase 4
NCT07446465 FOLFOX Chemotherapy Combined With Fruquintinib and Serplulimab as First-Line Conversion… Colorectal Cancer (Locally Advanced or Metastatic) Not Yet Recruiting
Phase 3
NCT07188025 ctDNA-Based Adjuvant Chemotherapy for High-Risk Rectal Cancer Rectal Cancer Recruiting
NCT07549399 SCRT + Chemo Targeted Immuno-neoadjuvant Therapy for High-risk pMMR/MSS RC Rectal Adenocarcinoma Not Yet Recruiting
NCT04793958 Phase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced… Advanced Colorectal Cancer Active, Not Recruiting
Phase 2/3
NCT06758830 Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer. Rectal Cancer Recruiting
Phase 2
NCT06162650 Total Neoadjuvant Therapy in Rectal Cancer Rectal Cancer Recruiting
NCT03921684 Trial of Nivolumab With FOLFOX After Chemoradiation in Rectal Cancer Patients Rectal Cancer Active, Not Recruiting
NCT07381400 Neoadjuvant mFOLFOX6 Chemotherapy Combined With Anti-PD-1 Therapy in MSS/pMMR Locally… Rectal Cancer Not Yet Recruiting
NCT05673772 Preoperative Sequential Short-course Radiation Therapy and FOLFOX for Locally Advanced… Rectal Cancer Active, Not Recruiting
NCT07450183 Perioperative Cemiplimab for Resectable Non-Small Cell Lung Cancer With High PD-L1 Lung Cancer (NSCLC) Not Yet Recruiting
NCT06890624 mFOLFOXIRI Plus PD-1 Inhibitor vs mFOLFOX6 as Neoadjuvant Therapy for Locally Advanced… Colon Cancer (Stage II &Amp;Amp; III) Not Yet Recruiting
Phase 1/2
NCT06445062 Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors Colorectal Cancer Recruiting
NCT06324357 Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in… Metastatic Breast Cancer Recruiting
Phase 1
NCT06917079 BBO-11818 in Adult Subjects With KRAS Mutant Cancer Non-Small Cell Lung Cancer Recruiting
NCT06835569 A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With… Cancer Recruiting
NCT07543471 A Phase I Multicentre Randomized Double-Blind Parallel-Controlled Study of HLX05-N vs… mCRC Not Yet Recruiting
Not specified
NCT03748485 Adjuvant Chemotherapy in Clinical Local Advanced CRC Following Preoperational Therapies… Colorectal Cancer Recruiting
NCT07413146 Neoadjuvant CAPEOX Versus Upfront Surgery for Locally Advanced Colon Cancer With Elevated… Minimal Residual Disease Not Yet Recruiting
Sponsors Running mFOLFOX6 Trials
Disease Areas
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