Drug Pipeline

Ifinatamab deruxtecan Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
17
Active Studies
14
Recruiting
3
Phase 3
3
Top Sponsors
2
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-02 NCT07405151
A Clinical Trial of Ifinatamab Deruxtecan in People With Advanced Esophageal Cancer…
Trial sites expanded: 7 -> 15 locations
2026-05-29 NCT04145622
Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid…
Trial sites expanded: 25 -> 28 locations
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-06-05 NCT07630974 A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory… Phase 1/2 Not Yet Recruiting
Active Studies by Phase
Phase 3
3
Phase 2
4
Phase 1/2
10
Active Trials
NCT IDTitleConditionStatus
Phase 3
NCT06644781 A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic… Esophageal Squamous Cell Carcinoma Recruiting
NCT06925737 A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate… Prostate Cancer Recruiting
NCT06203210 A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With… Small Cell Lung Cancer Recruiting
Phase 2
NCT06330064 A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects… Recurrent or Metastatic Solid Tumors Recruiting
NCT06780085 A Study of Investigational Agents in Participants With Previously Treated Stage IV… Carcinoma, Non-Small-Cell Lung Recruiting
NCT06780098 Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated… Lung Neoplasm Recruiting
NCT05280470 Ifinatamab Deruxtecan (I-DXd) in Subjects With Pretreated Extensive-Stage Small Cell Lung… Extensive-stage Small-cell Lung Cancer Active, Not Recruiting
Phase 1/2
NCT06362252 A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as… Extensive Stage-small Cell Lung Cancer Recruiting
NCT06780111 Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer… Esophageal Squamous Cell Carcinoma Recruiting
NCT06780137 A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab… Small Cell Lung Cancer Recruiting
NCT04165070 KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or… Carcinoma, Non-Small-Cell Lung Recruiting
NCT07227597 A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People… Small Cell Lung Cancer Extensive Stage Recruiting
NCT04145622 Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid… Advanced Solid Tumor Recruiting
NCT06863272 A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy… Castration-Resistant Prostatic Cancer Recruiting
NCT07405151 A Clinical Trial of Ifinatamab Deruxtecan in People With Advanced Esophageal Cancer… Oesophageal Squamous Cell Carcinoma Recruiting
NCT04471727 A Study in Participants With Advanced Cancers Associated With Expression of DLL3… Small-Cell Lung Cancer Active, Not Recruiting
NCT07630974 A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory… Malignant Neoplasm Not Yet Recruiting
Sponsors Running Ifinatamab deruxtecan Trials
Disease Areas
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