| Detected | Trial | Change |
|---|---|---|
| 2026-05-23 | NCT04961996 A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With… |
date change Completion moved earlier: 2035-01-01 -> 2033-09-30 |
| 2026-05-19 | NCT07100106 A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant… |
Trial sites expanded: 35 -> 39 locations |
| 2026-05-16 | NCT03332797 A Study of GDC-9545 Alone or in Combination With Palbociclib and/or Luteinizing… |
date change Primary completion pushed: 2026-07-31 -> 2027-07-31 |
| 2026-05-16 | NCT03332797 A Study of GDC-9545 Alone or in Combination With Palbociclib and/or Luteinizing… |
date change Completion pushed: 2026-07-31 -> 2027-07-31 |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT06065748 | A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a… | Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer | Recruiting |
| NCT05296798 | A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo… | Locally Advanced or Metastatic Breast Cancer | Active, Not Recruiting |
| NCT05306340 | A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With… | Estrogen Receptor (ER)-Positive, HER2-negative, Locally Advanced or Metastatic Breast Cancer | Active, Not Recruiting |
| NCT04546009 | A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib… | Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer | Active, Not Recruiting |
| NCT07541079 | A Study Evaluating Adherence, Tolerability, and Patient Reported Outcomes of Giredestrant… | Early Breast Cancer | Not Yet Recruiting |
| NCT04961996 | A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With… | Early Breast Cancer | Active, Not Recruiting |
| Phase 2 | |||
| NCT05708235 | A PoC Study to Evaluate Treatments' Efficacy by Monitoring MRD Using ctDNA in… | Breast Cancer | Recruiting |
| NCT04576455 | A Study Evaluating the Efficacy and Safety of Giredestrant Compared With Physician's… | Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer | Active, Not Recruiting |
| NCT05634499 | A Study of Giredestrant in Participants With Grade 1 Endometrial Cancer | Endometrial Cancer | Active, Not Recruiting |
| NCT04931342 | A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With… | Ovarian Cancer | Active, Not Recruiting |
| Phase 1/2 | |||
| NCT04486352 | A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer | Endometrial Cancer | Recruiting |
| NCT07100106 | A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant… | Breast Cancer | Recruiting |
| NCT04802759 | A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in… | Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer | Recruiting |
| Phase 1 | |||
| NCT07214662 | A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-0587 as a… | Breast Cancer | Recruiting |
| NCT03332797 | A Study of GDC-9545 Alone or in Combination With Palbociclib and/or Luteinizing… | Breast Cancer | Active, Not Recruiting |