| Detected | Trial | Change |
|---|---|---|
| 2026-06-06 | NCT07412470 A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults… |
Trial sites expanded: 16 -> 23 locations |
| 2026-05-30 | NCT07325292 Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous… |
Trial sites expanded: 24 -> 32 locations |
| 2026-05-21 | NCT07412470 A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults… |
Trial sites expanded: 10 -> 16 locations |
| 2026-05-16 | NCT07325292 Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous… |
Trial sites expanded: 18 -> 24 locations |
| 2026-05-15 | NCT06141473 Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of… |
overall status: "Recruiting" → "Active Not Recruiting" |
| 2026-05-15 | NCT06141486 Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary… |
overall status: "Recruiting" → "Active Not Recruiting" |
| 2026-05-15 | NCT06141486 Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary… |
Trial sites reduced: 338 -> 311 locations |
| 2026-05-15 | NCT06141486 Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary… |
date change Primary completion pushed: 2026-12-23 -> 2028-03-24 |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT07325292 | Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous… | Multiple Sclerosis | Recruiting |
| NCT06141473 | Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of… | Multiple Sclerosis | Active, Not Recruiting |
| NCT06141486 | Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary… | Multiple Sclerosis | Active, Not Recruiting |
| Phase 2/3 | |||
| NCT07412470 | A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults… | Kidney Transplant Rejection | Recruiting |
| Phase 2 | |||
| NCT06111586 | FrexalimAB in Preservation of Endogenous insULIN Secretion Compared to Placebo in adUlts… | Type 1 Diabetes Mellitus | Recruiting |
| NCT06500702 | A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib… | Focal Segmental Glomerulosclerosis | Recruiting |