Drug Pipeline

Enasidenib Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
17
Active Studies
14
Recruiting
10
Top Sponsors
1
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-03 NCT06672146
Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has…
Trial sites expanded: 127 -> 130 locations
Active Studies by Phase
Phase 2
11
Phase 1/2
3
Phase 1
3
Active Trials
NCT IDTitleConditionStatus
Phase 2
NCT03383575 Azacitidine and Enasidenib in Treating Patients With IDH2-Mutant Myelodysplastic Syndrome Acute Myeloid Leukemia Recruiting
NCT03683433 Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute… Acute Bilineal Leukemia Recruiting
NCT06756308 A Study of Enasidenib in People With T-Cell Lymphoma T-cell Lymphoma Recruiting
NCT03728335 Enasidenib (AG-221) Maintenance Post Allogeneic HCT in Patients With IDH2 Mutation Acute Myeloid Leukemia Recruiting
NCT06240754 Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations… Clonal Cytopenia of Undetermined Significance Recruiting
NCT06176989 Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base Tumors Metastatic Chondrosarcoma Recruiting
NCT05401097 IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of… Acute Myeloid Leukemia Recruiting
NCT05564390 MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study… Acute Myeloid Leukemia Recruiting
NCT06577441 Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment… Myelodysplastic Syndrome Recruiting
NCT06672146 Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has… Acute Myeloid Leukemia Recruiting
NCT04203316 Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients… Recurrent Acute Myeloid Leukemia Active, Not Recruiting
Phase 1/2
NCT02813135 European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in… Pediatric Cancer Recruiting
NCT04774393 Decitabine/Cedazuridine and Venetoclax in Combination With Ivosidenib or Enasidenib for… Acute Myeloid Leukemia Recruiting
NCT02677922 A Study to Assess the Safety and Efficacy of Two Combinations of Isocitrate Dehydrogenase… Leukemia, Myeloid, Acute Active, Not Recruiting
Phase 1
NCT05010772 Decitabine Alone or in Combination With Venetoclax, Gilteritinib, Enasidenib, or… Acute Myeloid Leukemia Recruiting
NCT05756777 A Study of Gilteritinib in Combination With Ivosidenib or Enasidenib in People With Acute… Acute Myeloid Leukemia (AML) Recruiting
NCT02632708 Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy… Newly Diagnosed Acute Myeloid Leukemia (AML) Active, Not Recruiting
Sponsors Running Enasidenib Trials
Disease Areas
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