Drug Pipeline

Cladribine Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
19
Active Studies
14
Recruiting
2
Phase 3
9
Top Sponsors
Active Studies by Phase
Phase 2/3
2
Phase 2
11
Phase 1/2
4
Phase 1
1
Not specified
1
Active Trials
NCT IDTitleConditionStatus
Phase 2/3
NCT04708054 Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With… Acute Myeloid Leukemia Recruiting
NCT02205762 LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With… Langerhans Cell Histiocytosis Active, Not Recruiting
Phase 2
NCT01515527 Cladribine Plus Low Dose Cytarabine (LDAC) Alternating With Decitabine in Patients With… Leukemia Recruiting
NCT06504459 Venetoclax in Combination With Cladribine and Cytarabine Alternating With Azacitidine… Acute Monocytic Leukemia Recruiting
NCT07032727 Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated… Targeted Therapy Recruiting
NCT02115295 Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute… Acute Biphenotypic Leukemia Recruiting
NCT03589729 Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in… Acute Myeloid Leukemia Recruiting
NCT06561360 A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People… Hairy Cell Leukemia Recruiting
NCT05365035 A Phase II Study of Cladribine and Low Dose Cytarabine in Combination With Venetoclax… Myelodysplastic Syndromes Recruiting
NCT03586609 Venetoclax, Cladribine, Low Dose Cytarabine, and Azacitidine in Treating Patients With… Acute Myeloid Leukemia Recruiting
NCT00412594 Cladribine and Rituximab in Treating Patients With Hairy Cell Leukemia Hairy Cell Leukemia Recruiting
NCT02250937 Venetoclax and Sequential Busulfan, Cladribine, and Fludarabine Phosphate Before Donor… Acute Myeloid Leukemia Active, Not Recruiting
NCT04195945 CPX-351 or CLAG-M Regimen for the Treatment of Acute Myeloid Leukemia or Other High-Grade… Acute Myeloid Leukemia Active, Not Recruiting
Phase 1/2
NCT06561152 Tagraxofusp and Low-Intensity Chemotherapy for CD123-Positive Relapsed or Refractory AML Refractory Acute Myeloid Leukemia Recruiting
NCT04797767 Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid… Acute Biphenotypic Leukemia Recruiting
NCT06965114 Testing the Combination of Anti-cancer Drugs, Tovorafenib Plus Rituximab, in Patients… Hairy Cell Leukemia Recruiting
NCT07311746 Phase Ib/II Trial of Cladribine/Ruxolitinib/Venetoclax in Patients With… T-cell Prolymphocytic Leukemia Not Yet Recruiting
Phase 1
NCT04375631 CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell… Recurrent Acute Myeloid Leukemia Recruiting
Not specified
NCT05797740 Cladribine Tablets Level of Response Predictors in Clinical Practice (CLODINA) Multiple Sclerosis Active, Not Recruiting
Sponsors Running Cladribine Trials
Disease Areas
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