Drug Pipeline

Carfilzomib Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
58
Active Studies
23
Recruiting
13
Phase 3
10
Top Sponsors
24
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-12 NCT07391657
A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA)…
Trial sites expanded: 111 -> 116 locations
2026-06-11 NCT07227311
A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With…
Trial sites expanded: 18 -> 27 locations
2026-06-06 NCT05438043
A Study of Daratumumab
date change Completion pushed: 2029-01-31 -> 2029-12-31
2026-06-06 NCT06152575
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People…
Trial sites reduced: 278 -> 271 locations
2026-06-04 NCT04430894
KRDI in Transplant-Eligible MM
date change Completion pushed: 2026-03-30 -> 2026-12-30
2026-06-03 NCT07227311
A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With…
Trial sites expanded: 12 -> 18 locations
2026-06-02 NCT05434689
COMbination Regimens in MM Post AHCT to elimiNate MRD Utilizing IbERdomide
date change Primary completion pushed: 2026-04 -> 2028-08
2026-06-02 NCT05434689
COMbination Regimens in MM Post AHCT to elimiNate MRD Utilizing IbERdomide
date change Completion pushed: 2026-10 -> 2028-08
2026-05-28 NCT03798678
CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With…
date change Primary completion pushed: 2023-11-08 -> 2026-09-11
2026-05-28 NCT03798678
CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With…
date change Completion pushed: 2023-11-08 -> 2026-09-11
2026-05-28 NCT07555938
Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in…
Recruitment opened
2026-05-28 NCT07555938
Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in…
Trial sites expanded: 0 -> 4 locations
2026-05-28 NCT07555938
Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in…
date change Primary completion moved earlier: 2029-06-29 -> 2028-10-31
2026-05-28 NCT07555938
Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in…
date change Completion pushed: 2032-12-31 -> 2033-01-31
2026-05-16 NCT07227311
A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With…
Trial sites expanded: 6 -> 10 locations
2026-05-15 NCT06152575
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People…
Trial sites expanded: 131 -> 279 locations
2026-05-15 NCT07479979
Study of Selinexor With Carfilzomib, Isatuximab and Dexamethasone for Patients With…
Recruitment opened
2026-05-14 NCT03798678
CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With…
Trial terminated
2026-05-14 NCT03798678
CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With…
critical why stopped: null → "Other - Drug supply issues and withdrawal of company support."
2026-05-14 NCT03798678
CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With…
Enrollment reduced: 36 -> 19 participants
Showing 20 of 24 changes detected in the last 30 days.
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-05-26 NCT07605416 Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM… Phase 2 Not Yet Recruiting
Active Studies by Phase
Phase 3
12
Phase 2/3
1
Phase 2
23
Phase 1/2
11
Phase 1
10
Not specified
1
Active Trials — top 25 of 58
NCT IDTitleConditionStatus
Phase 3
NCT06413498 A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants… Multiple Myeloma Recruiting
NCT07555938 Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in… Multiple Myeloma Recruiting
NCT07222761 A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination… Relapsed and/or Refractory Multiple Myeloma (RRMM) Recruiting
NCT06615479 A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in… Relapsed or Refractory Multiple Myeloma (RRMM) Recruiting
NCT05438043 A Study of Daratumumab Multiple Myeloma Recruiting
NCT06152575 MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People… Multiple Myeloma Recruiting
NCT06158841 Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard… Multiple Myeloma Recruiting
NCT07391657 A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA)… Relapsed Refractory Multiple Myeloma Recruiting
NCT02659293 Trial of Carfilzomib, Lenalidomide, Dexamethasone Versus Lenalidomide Alone After… Multiple Myeloma Active, Not Recruiting
NCT03729804 Carfilzomib, Lenalidomide, and Dexamethasone Versus Bortezomib, Lenalidomide and… Multiple Myeloma Active, Not Recruiting
NCT05552976 A Study to Evaluate Mezigdomide in Combination With Carfilzomib and Dexamethasone… Relapsed or Refractory Multiple Myeloma Active, Not Recruiting
NCT05572515 A Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone… Relapsed or Refractory Multiple Myeloma Active, Not Recruiting
Phase 2/3
NCT04310930 Finding the Optimal Regimen for Mycobacterium Abscessus Treatment Pulmonary Disease Due to Mycobacteria (Diagnosis) Recruiting
Phase 2
NCT06627751 Mezigdomide, Carfilzomib, and Dexamethasone for the Treatment of Relapsed or Refractory… Extramedullary Disease in Multiple Myeloma Recruiting
NCT06356571 A Study to Investigate Subcutaneous Isatuximab in Combination With Weekly Carfilzomib and… Plasma Cell Myeloma Refractory Recruiting
NCT05896228 Iberdomide, Daratumumab, Carfilzomib, and Dexamethasone (Iber-KDd) in Patients With… Refractory Multiple Myeloma Recruiting
NCT07227311 A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With… Multiple Myeloma Recruiting
NCT05704049 A Study to Investigate Subcutaneous Isatuximab in Combination With Carfilzomib and… Relapsed/Refractory Multiple Myeloma Active, Not Recruiting
NCT05556746 Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard… Tuberculosis, Pulmonary Active, Not Recruiting
NCT04883242 Isatuximab, Carfilzomib, Pomalidomide, and Dexamethasone for the Treatment of Relapsed or… Recurrent Multiple Myeloma Active, Not Recruiting
NCT07485010 Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase… Mycobacterium Abscessus Pulmonary Disease Not Yet Recruiting
NCT04268498 A Study of Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone in Patients With… Multiple Myeloma Active, Not Recruiting
NCT04925193 Personalized Selinexor-based Therapy for Relapsed/Refractory Multiple Myeloma Multiple Myeloma in Relapse Active, Not Recruiting
NCT03500445 Daratumumab, Carfilzomib, Lenalidomide and Low Dose Dexamethasone (DKRd) in Newly… Myeloma Active, Not Recruiting
NCT03828201 Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and… Tuberculosis, Multidrug-Resistant Active, Not Recruiting
Sponsors Running Carfilzomib Trials
Disease Areas
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