Drug Pipeline

Apalutamide Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
41
Active Studies
15
Recruiting
14
Phase 3
10
Top Sponsors
3
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-10 NCT06592924
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration…
Trial sites expanded: 340 -> 368 locations
2026-06-03 NCT06931340
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy…
Trial sites expanded: 186 -> 194 locations
2026-05-16 NCT04423211
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted…
Trial sites expanded: 303 -> 342 locations
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-05-28 NCT07611110 AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant… Phase 3 Recruiting
Active Studies by Phase
Phase 4
1
Phase 3
14
Phase 2
15
Phase 1/2
3
Phase 1
6
Not specified
2
Active Trials — top 25 of 41
NCT IDTitleConditionStatus
Phase 4
NCT04108208 A Study of Apalutamide in Chinese Participants With Non Metastatic Castration Resistant… Prostatic Neoplasms Active, Not Recruiting
Phase 3
NCT04134260 Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation… Prostate Adenocarcinoma Recruiting
NCT04423211 Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted… Biochemically Recurrent Prostate Carcinoma Recruiting
NCT06274047 PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and… Androgen Axis Suppression Recruiting
NCT07611110 AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant… Metastatic Castration-resistant Prostate Cancer Recruiting
NCT06931340 Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy… Castration-Sensitive Prostate Carcinoma Recruiting
NCT06592924 Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration… Prostate Cancer (Adenocarcinoma) Recruiting
NCT04513717 Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment… Prostate Adenocarcinoma Active, Not Recruiting
NCT01946204 A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate… Prostatic Neoplasms Active, Not Recruiting
NCT02257736 An Efficacy and Safety Study of Apalutamide (JNJ-56021927) in Combination With… Prostatic Neoplasms Active, Not Recruiting
NCT02489318 A Study of Apalutamide (JNJ-56021927, ARN-509) Plus Androgen Deprivation Therapy (ADT)… Prostate Cancer Active, Not Recruiting
NCT02531516 An Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer… Prostatic Neoplasms Active, Not Recruiting
NCT03767244 A Study of Apalutamide in Participants With High-Risk, Localized or Locally Advanced… Prostatic Neoplasms Active, Not Recruiting
NCT04557059 A Study of Adding Apalutamide to Radiotherapy and LHRH Agonist in High-Risk Patients With… Prostatic Neoplasms Active, Not Recruiting
NCT05884398 A Study of an Intermittent ADT Approach With Apalutamide Monotherapy in Participants With… Metastatic Castrate-sensitive Prostate Cancer Active, Not Recruiting
Phase 2
NCT05534646 Study of Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer Castration-resistant Prostate Cancer Recruiting
NCT05751941 Study of Sipuleucel-T With or Without Continuing New Hormonal Agents in Metastatic… Prostate Cancer Recruiting
NCT06378866 Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway… Recurrent Castration-Sensitive Prostate Carcinoma Recruiting
NCT04947254 Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the… Prostate Carcinoma Recruiting
NCT02949284 Androgen Receptor Antagonist ARN-509 With or Without Abiraterone Acetate… Stage II Prostate Adenocarcinoma Active, Not Recruiting
NCT03371719 Radiation Therapy With or Without Apalutamide in Treating Patients With Recurrent… Recurrent Prostate Carcinoma Active, Not Recruiting
NCT04267887 Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer Castration-Sensitive Prostate Carcinoma Active, Not Recruiting
NCT03902951 Antiandrogen Therapy and SBRT in Treating Patients With Recurrent, Metastatic Prostate… Metastatic Prostate Adenocarcinoma Active, Not Recruiting
NCT02703623 Abiraterone Acetate, Prednisone, and Apalutamide With or Without Ipilimumab or… Castration Levels of Testosterone Active, Not Recruiting
NCT03412396 Apalutamide in Treating Patients With Prostate Cancer Before Radical Prostatectomy Prostate Adenocarcinoma Active, Not Recruiting
Sponsors Running Apalutamide Trials
Disease Areas
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