Drug Pipeline

AK117 Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
4
Active Studies
2
Recruiting
1
Phase 3
3
Top Sponsors
2
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-21 NCT07264075
Study Comparing Ivonescimab Alone or Ivonescimab in Combination With Ligufalimab Versus…		 Recruitment opened
2026-05-21 NCT07264075
Study Comparing Ivonescimab Alone or Ivonescimab in Combination With Ligufalimab Versus…		 date change Primary completion pushed: 2030-01 -> 2030-05
Active Studies by Phase
Phase 3
1
Phase 2
2
Phase 1/2
1
Active Trials
NCT IDTitleConditionStatus
Phase 3
NCT07264075 Study Comparing Ivonescimab Alone or Ivonescimab in Combination With Ligufalimab Versus… Squamous Cell Carcinoma Head and Neck Cancer (HNSCC) Recruiting
Phase 2
NCT06789848 Ligufalimab and Cadonilimab in Advanced Liver Cancers Advanced Hepatocellular Carcinoma Recruiting
NCT05227664 A Study of AK117/AK112 in Metastatic Triple-Negative Breast Cancer Metastatic Triple-negative Breast Cancer Active, Not Recruiting
Phase 1/2
NCT05229497 A Phase Ib/II Study of AK112 in Combination With AK117 in Advanced Malignant Tumors Advanced Malignant Tumors Active, Not Recruiting
Sponsors Running AK117 Trials
Akeso (2) University of Texas Southwestern Medical Center (1) Groupe Oncologie Radiotherapie Tete et Cou (1)
Disease Areas
Breast Cancer (1) Triple-Negative Breast Cancer (1) Liver Cancer (1) Cholangiocarcinoma (1) Head & Neck Cancer (1)
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