Disease landscape

Idiopathic Pulmonary Fibrosis clinical trials

Get alerts when Idiopathic Pulmonary Fibrosis trials change

141 active trials 75 recruiting 15 Phase 3 103 sponsors 21 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-09-16

What changed in the last 30 days

2026-09-04
Primary completion pushed: 2029-06 → 2029-11
Completion pushed: 2029-07 → 2029-12
NCT07284602 Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to… · PureTech · Phase 3
2026-09-03
Primary completion pushed: 2027-01 → 2028-01
Completion pushed: 2027-01 → 2028-01
NCT05571059 Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF) · Cumberland Pharmaceuticals · Phase 2
2026-09-03
Primary completion pushed: 2028-02-12 → 2028-06-27
Completion pushed: 2028-02-12 → 2028-06-27
NCT07516951 A Study to Find an Efficacious and Safe Dose of CHF10067 (Zampilimab) in Participants… · Chiesi Farmaceutici S.p.A. · Phase 2
2026-09-15
Enrollment reduced: 210 → 153 participants
Primary completion moved earlier: 2028-01-30 → 2027-12-30
Completion moved earlier: 2028-12 → 2028-06
NCT07679893 Phase 2 Clinical Trial of MNKD-201 (Nintedanib Dry Powder Inhalation) in Patients With… · Mannkind Corporation · Phase 2
2026-08-22
Trial completed
NCT06241560 A Study in People With Idiopathic Pulmonary Fibrosis to Test Whether Pirfenidone… · Boehringer Ingelheim · Phase 2
2026-08-25
Trial completed
Completion moved earlier: 2029-09-30 → 2025-10-17
NCT04071769 Genentech Xenon MRI Idiopathic Pulmonary Fibrosis · Duke University · Phase 2
2026-09-15
Trial sites expanded: 15 → 19 locations
NCT07671911 Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine… · Trevi Therapeutics · Phase 3
2026-09-01
Trial sites expanded: 5 → 15 locations
NCT07671911 Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine… · Trevi Therapeutics · Phase 3
2026-09-03
Trial sites expanded: 49 → 56 locations
NCT07230288 Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult… · AbbVie · Phase 2
2026-08-29
Trial sites expanded: 68 → 72 locations
NCT06951217 An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL) · Avalyn Pharma Inc. · Phase 2
2026-08-25
Trial sites expanded: 6 → 49 locations
NCT07230288 Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult… · AbbVie · Phase 2
2026-08-21
Trial sites expanded: 65 → 68 locations
NCT07284459 Study to Evaluate the Efficacy, Safety, and Tolerability of PIPE 791 in Subjects With… · Contineum Therapeutics · Phase 2
2026-08-18
Trial sites reduced: 111 → 104 locations
NCT06588686 A Trial to Evaluate Efficacy and Safety of Buloxibutid in People With Idiopathic… · Vicore Pharma AB · Phase 2
2026-09-09
Trial sites expanded: 1 → 15 locations
NCT07520110 Metformin to Attenuate Progressive Respiratory Decline in Idiopathic Pulmonary Fibrosis · University of Massachusetts, Worcester · Phase 3
2026-09-06
Trial status changed: Not Yet Recruiting → Unknown
NCT06521125 Clinical Genetics and Screening for Idiopathic Pulmonary Fibrosis · Fondazione Policlinico Universitario Agostino Gemelli IRCCS

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-09-15 NCT07820254 Inspiratory Flow Rate Capability in Pulmonary Fibrosis Patients Shanghai Pulmonary Hospital, Shanghai, China new
2026-07-22 NCT07719023 A Phase 3 Study of Efficacy and Safety of AK3280 in Patients With Idiopathic Pulmonary… Shanghai Ark Biopharmaceutical Co., Ltd. new Phase 3
2026-07-16 NCT07707245 Identification of Diagnostic and Prognostic Biomarkers in the Pathological Continuum of… Fondazione Don Carlo Gnocchi ETS new
2026-07-07 NCT07687459 Study Evaluation Rentosertib (INS018_055) Administered Orally in Patients With Idiopathic… InSilico Medicine Hong Kong Limited new Phase 3
2026-07-07 NCT07686562 Artificial Intelligence (AI) Detection of Incidental Interstitial Opacity on Chest… Chung-Ang University Hospital new
2026-07-02 NCT07682337 Study of Single and Multiple Oral Doses of SCB0020160 in Healthy Adult Male Subjects SCBIO Inc. new Phase 1
2026-06-29 NCT07673237 Remote Evaluation and Surveillance of Patients With Interstitial Lung Disease… University of California, San Francisco new

Active trials by phase

Early Phase 1
3
Phase 1
14
Phase 1/2
2
Phase 2
36
Phase 2/3
1
Phase 3
14
Not charted: 71 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 141

NCT IDTitleSponsorStatusUpdated
Phase 3
NCT07671911 Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine… Trevi Therapeutics Recruiting 2026-09-14
NCT07284602 Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to… PureTech Recruiting 2026-09-03
NCT06238622 A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary… Boehringer Ingelheim Recruiting 2026-08-20
NCT07082842 Confirmatory Clinical Study of HEC585 Tablets in Patients With IPF Sunshine Lake Pharma Co., Ltd. Recruiting 2026-04-21
NCT07299695 Intravenous Immunoglobulin for the Treatment of Acute Exacerbations of Idiopathic… Argyrios Tzouvelekis Recruiting 2026-03-16
NCT07464912 A Adaptive Design Clinical Trial to Evaluate the Efficacy and Safety of TDI01 Suspension… Beijing Tide Pharmaceutical Co., Ltd Recruiting 2026-03-11
NCT05674994 Glucocorticoids Versus Placebo for the Treatment of Acute Exacerbation of Idiopathic… Fondation Hôpital Saint-Joseph Recruiting 2026-03-02
NCT04965298 Treating People With Idiopathic Pulmonary Fibrosis With the Addition of Lansoprazole Norfolk and Norwich University Hospitals NHS Foundation Trust Recruiting 2025-12-22
NCT07520110 Metformin to Attenuate Progressive Respiratory Decline in Idiopathic Pulmonary Fibrosis University of Massachusetts, Worcester Not Yet Recruiting 2026-09-08
NCT04905693 Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease United Therapeutics Enrolling by Invitation 2026-09-03
NCT07719023 A Phase 3 Study of Efficacy and Safety of AK3280 in Patients With Idiopathic Pulmonary… Shanghai Ark Biopharmaceutical Co., Ltd. Not Yet Recruiting 2026-07-22
NCT07687459 Study Evaluation Rentosertib (INS018_055) Administered Orally in Patients With Idiopathic… InSilico Medicine Hong Kong Limited Not Yet Recruiting 2026-07-07
NCT07519070 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study to Evaluate… Haisco Pharmaceutical Group Co., Ltd. Not Yet Recruiting 2026-04-09
NCT06003426 A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants… Bristol-Myers Squibb Active, Not Recruiting 2026-03-24
Phase 2/3
NCT06125327 SC1011 Twice Daily vs Placebo in Patients Diagnosed With Idiopathic Pulmonary Fibrosis… Guangzhou JOYO Pharma Co., Ltd Recruiting 2024-11-19
Phase 2
NCT07679893 Phase 2 Clinical Trial of MNKD-201 (Nintedanib Dry Powder Inhalation) in Patients With… Mannkind Corporation Recruiting 2026-09-14
NCT07284459 Study to Evaluate the Efficacy, Safety, and Tolerability of PIPE 791 in Subjects With… Contineum Therapeutics Recruiting 2026-09-11
NCT06968845 A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis Rein Therapeutics Recruiting 2026-09-04
NCT07230288 Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult… AbbVie Recruiting 2026-09-03
NCT05571059 Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF) Cumberland Pharmaceuticals Recruiting 2026-09-02
NCT07036523 A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With… Boehringer Ingelheim Recruiting 2026-09-02
NCT07516951 A Study to Find an Efficacious and Safe Dose of CHF10067 (Zampilimab) in Participants… Chiesi Farmaceutici S.p.A. Recruiting 2026-09-02
NCT06951217 An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL) Avalyn Pharma Inc. Recruiting 2026-08-28
NCT06967805 WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF) Mediar Therapeutics Recruiting 2026-08-10
NCT07194382 AURA-IPF: A Randomized Phase 2 Study to Evaluate the Safety and Efficacy of AP02… Avalyn Pharma Inc. Recruiting 2026-08-10
See all 141 active Idiopathic Pulmonary Fibrosis trials with filters →

Top sponsors by active trials in this area

Assiut University (5) · Boehringer Ingelheim (3) · Haisco Pharmaceutical Group Co., Ltd. (3) · Henan University of Traditional Chinese Medicine (3) · Hospital de Granollers (3) · Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (3) · Istituto Clinico Humanitas (3) · University of Virginia (3) · Avalyn Pharma Inc. (2) · Bristol-Myers Squibb (2)

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