Disease landscape

IgA Nephropathy clinical trials

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91 active trials 48 recruiting 21 Phase 3 65 sponsors 10 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days

2026-08-15
notable
Enrollment closed, study ongoing
Trial sites reduced: 204 → 178 locations
NCT05797610 A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants… · Hoffmann-La Roche · Phase 3
2026-08-09
notable
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University → Second Affiliated Hospital, Zhejiang University, School of Medicine
NCT05596708 Study of Telitacicept in Patients With Refractory IgA Nephropathy · Second Affiliated Hospital, School of Medicine, Zhejiang University · Phase 2/3
2026-08-05
notable
Recruitment opened
NCT06419205 A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in… · Akebia Therapeutics · Phase 2
2026-08-04
minor
Enrollment increased: 84 → 96 participants
NCT07203404 A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With… · Nanjing Bioheng Biotech Co., Ltd. · Early Phase 1
2026-08-21
minor
Trial sites expanded: 9 → 15 locations
NCT07541287 A Study of JADE101 in Participants With Immunoglobulin A Nephropathy · Jade Biosciences, Inc. · Phase 2
2026-08-18
minor
Trial sites expanded: 21 → 26 locations
NCT06858319 Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy. · Novartis Pharmaceuticals · Phase 3
2026-08-08
minor
Trial sites expanded: 6 → 9 locations
NCT07498335 Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Atrasentan in… · Novartis Pharmaceuticals · Phase 3
2026-08-01
minor
Trial sites expanded: 172 → 175 locations
NCT06963827 A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy · Takeda · Phase 3
2026-08-11
minor
Trial sites expanded: 26 → 29 locations
NCT07146906 A Study to Assess the Effects of Zigakibart on IgA Nephropathy. · Novartis Pharmaceuticals · Phase 2

Active trials by phase

Early Phase 1
10
Phase 1
4
Phase 1/2
3
Phase 2
27
Phase 2/3
2
Phase 3
19
Phase 4
5
Not charted: 21 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 91

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT06712407 Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With… Calliditas Therapeutics AB Recruiting 2026-02-05
NCT07030894 Nefecon and Ambrisentan in IgA Nephropathy The First Hospital of Jilin University Recruiting 2025-09-15
NCT06676384 Which of the Commonly Available and Approved Drugs in Addition to Standard of Care Can… Christian Medical College, Vellore, India Recruiting 2025-07-14
NCT07604311 Efficacy and Safety of Nefecon on Prevention of Relapse of IgA Nephropathy: a Randomized… Nanfang Hospital, Southern Medical University Not Yet Recruiting 2026-05-22
NCT06528015 Efficacy and Safety of Probiotics Combined With Enteric-coated Budesonide Capsules in… Gang Xu Not Yet Recruiting 2024-07-30
Phase 3
NCT06858319 Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy. Novartis Pharmaceuticals Recruiting 2026-08-17
NCT06963827 A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy Takeda Recruiting 2026-08-14
NCT07498335 Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Atrasentan in… Novartis Pharmaceuticals Recruiting 2026-08-07
NCT07390123 Phase Ⅲ Study of Efficacy and Safety of HSK39297 Tablet in Treatment of Patients With… Haisco Pharmaceutical Group Co., Ltd. Recruiting 2026-05-28
NCT07014826 A Trial of HRS-5965 Capsule in Primary IgA Nephropathy Chengdu Suncadia Medicine Co., Ltd. Recruiting 2025-08-05
NCT06819826 A Study of SC0062 Capsule for the Treatment of IgA Nephropathy with Proteinuria Biocity Biopharmaceutics Co., Ltd. Recruiting 2025-02-17
NCT05510323 Efficacy of Immunosuppressive Therapy for IgA Nephropathy With Stage 3 or 4 CKD Air Force Military Medical University, China Recruiting 2024-05-06
NCT07770815 Trial of Sibeprenlimab in Children and Adolescents With Immunoglobulin A Nephropathy… Otsuka Pharmaceutical Development & Commercialization, Inc. Not Yet Recruiting 2026-08-18
NCT05797610 A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants… Hoffmann-La Roche Active, Not Recruiting 2026-08-14
NCT04557462 A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of… Novartis Pharmaceuticals Active, Not Recruiting 2026-07-30
NCT07642050 A Study to Determine if BHV-1400 is Effective and Safe in Adults With IgA Nephropathy Biohaven Therapeutics Ltd. Not Yet Recruiting 2026-06-11
NCT04573478 Atrasentan in Patients With IgA Nephropathy Novartis Pharmaceuticals Active, Not Recruiting 2026-06-04
NCT03762850 A Study of the Effect and Safety of Sparsentan in the Treatment of Patients With IgA… Travere Therapeutics, Inc. Active, Not Recruiting 2026-04-20
NCT05852938 A Study of Zigakibart in Adults With IgA Nephropathy Novartis Pharmaceuticals Active, Not Recruiting 2026-04-01
NCT05799287 A Study of Telitacicept for IgA Nephropathy (TELIGAN) RemeGen Co., Ltd. Active, Not Recruiting 2025-12-16
NCT04716231 Atacicept in Subjects With IgA Nephropathy Vera Therapeutics, Inc. Active, Not Recruiting 2025-09-30
NCT07098897 To Evaluate the Effect and Safety of Telitacicept and Standard Treatment for 6months in… The Affiliated Hospital of Xuzhou Medical University Active, Not Recruiting 2025-08-01
NCT07052981 Clinical Study on the Efficacy and Safety of Telitacicept in the Treatment of Pediatric… Guixia Ding Not Yet Recruiting 2025-07-10
NCT06580288 Effect of Finerenone in IgA Nephropathy Zhejiang University Not Yet Recruiting 2024-08-30
Phase 2/3
NCT03418779 Treatment Effects of Chinese Medicine (Yi-Qi-Qing-Jie Herbal Compound) Combined With… Guang'anmen Hospital of China Academy of Chinese Medical Sciences Active, Not Recruiting 2024-09-25

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