Disease landscape

Hidradenitis Suppurativa clinical trials

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94 active trials 53 recruiting 14 Phase 3 57 sponsors 23 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days

2026-08-28
critical
Primary completion pushed: 2025-10-30 → 2028-10-30
Recruitment opened
Completion pushed: 2025-12-30 → 2028-12-30
NCT06932003 A Study to Explore the Safety, Tolerability, Efficacy, and Pharmacokinetics of LT-002-158… · Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. · Phase 1/2
2026-08-28
critical
Primary completion pushed: 2025-03-31 → 2025-11-25
Trial completed
Enrollment increased: 127 → 150 participants
Completion pushed: 2025-06-01 → 2025-11-25
NCT06082323 A Single and Multiple Ascending Dose Trial of LT-002-158 Tablets in Healthy Adult… · Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. · Phase 1
2026-08-22
notable
Trial completed
NCT04179175 Extension Study to Assess Effects of Non-interrupted Versus Interrupted and Long Term… · Novartis Pharmaceuticals · Phase 3
2026-08-22
notable
Trial completed
NCT04901195 A Study to Test the Long-term Treatment of Bimekizumab in Study Participants With… · UCB Biopharma SRL · Phase 3
2026-08-22
notable
Trial completed
NCT06046729 A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe… · Eli Lilly and Company · Phase 2
2026-08-18
notable
Recruitment opened
NCT07547813 A Proof-of-Concept Study of LAD328 in Adults With Hidradenitis Suppurativa · Almirall, S.A. · Phase 2
2026-08-15
notable
Enrollment closed, study ongoing
NCT05889182 A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in… · AbbVie · Phase 3
2026-08-01
notable
Enrollment closed, study ongoing
NCT06921850 A Study to Assess the Pharmacokinetics and Safety of Bimekizumab in Children and… · UCB Biopharma SRL · Phase 3
2026-08-09
notable
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University → Second Affiliated Hospital, Zhejiang University, School of Medicine
NCT07554014 A Single-center, Prospective, Self-controlled, Observational Real-world Study of the… · Second Affiliated Hospital, School of Medicine, Zhejiang University · Phase 4
2026-08-09
notable
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University → Second Affiliated Hospital, Zhejiang University, School of Medicine
NCT06707246 A Randomized Trial Comparing the Efficacy and Safety of Secukinumab with Tofacitinib in… · Second Affiliated Hospital, School of Medicine, Zhejiang University
2026-08-04
notable
Trial completed
Completion pushed: 2026-04 → 2026-07-15
NCT06374212 Anifrolumab for Hidradenitis Suppurativa · University of North Carolina, Chapel Hill · Phase 2
2026-08-19
minor
Trial sites expanded: 4 → 11 locations
NCT07665437 An Extension Study to Assess Safety and Efficacy of Remibrutinib in Participants With… · Novartis Pharmaceuticals · Phase 3
2026-08-19
minor
Trial sites expanded: 7 → 10 locations
NCT07489573 Study of Efficacy and Safety of Secukinumab in Chinese Adult Patients With Moderate to… · Novartis Pharmaceuticals · Phase 4
2026-08-26
minor
Primary completion moved earlier: 2026-11-16 → 2026-04-02
Completion moved earlier: 2029-01-22 → 2028-06-06
NCT06956235 Study to Evaluate Tulisokibart for Hidradenitis Suppurativa (MK-7240-012) · Merck Sharp & Dohme LLC · Phase 2
2026-08-21
minor
Primary completion moved earlier: 2027-08-01 → 2027-02-09
Completion pushed: 2028-04-27 → 2029-11-23
NCT07170917 Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa · Sanofi · Phase 2

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-08-24 NCT07783542 ORKA-002 Versus Placebo in Participants With Moderate-to-Severe Hidradenitis Suppurativa Oruka Therapeutics, Inc. new Phase 2
2026-08-14 NCT07766005 A Study of SPY072 in Adults With Moderate to Severe Hidradenitis Suppurativa (The… Spyre Therapeutics, Inc. new Phase 2
2026-08-10 NCT07755670 Exploration of Brain Functional Networks in Patients With Hidradenitis Suppurativa Using… Second Xiangya Hospital of Central South University new
2026-07-16 NCT07708480 Comparative Efficacy of Apremilast and Acitretin in Moderate-to-Severe Hidradenitis… Hayat Abad Medical Complex, Peshawar new Phase 4
2026-07-08 NCT07689188 Safety and Efficacy of Roflumilast Foam 0.3% in Adolescent and Adult Subjects With… Harrison Dermatology new Phase 2
2026-06-25 NCT07668713 FEcal tranSplantation in HidradeniTIs suppuratiVA : a piLot Study University Hospital, Clermont-Ferrand new Phase 1
2026-06-22 NCT07659769 Global Healthcare Study on Hidradenitis Suppurativa Julia Tatjana Maul new

Active trials by phase

Early Phase 1
3
Phase 1
7
Phase 1/2
2
Phase 2
23
Phase 2/3
1
Phase 3
13
Phase 4
3
Not charted: 42 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 94

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07489573 Study of Efficacy and Safety of Secukinumab in Chinese Adult Patients With Moderate to… Novartis Pharmaceuticals Recruiting 2026-08-18
NCT07554014 A Single-center, Prospective, Self-controlled, Observational Real-world Study of the… Second Affiliated Hospital, School of Medicine, Zhejiang University Not Yet Recruiting 2026-04-28
NCT07261072 Comparison of the Clinical Efficacy and Safety of Topical and Subcutaneous Injection of… Peking Union Medical College Not Yet Recruiting 2025-12-03
Phase 3
NCT07665437 An Extension Study to Assess Safety and Efficacy of Remibrutinib in Participants With… Novartis Pharmaceuticals Recruiting 2026-08-18
NCT06855498 Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib Incyte Corporation Recruiting 2026-08-06
NCT05821478 Efficacy of an Adapted Antibiotherapy in Hurley Stage 2 Hidradenitis Suppurativa Patients Institut Pasteur Recruiting 2025-07-09
NCT06212999 A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants… Incyte Corporation Active, Not Recruiting 2026-08-25
NCT06468228 A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent… AbbVie Active, Not Recruiting 2026-08-21
NCT06840392 A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and… Novartis Pharmaceuticals Active, Not Recruiting 2026-08-21
NCT05889182 A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in… AbbVie Active, Not Recruiting 2026-08-20
NCT06799000 A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and… Novartis Pharmaceuticals Active, Not Recruiting 2026-08-20
NCT06921850 A Study to Assess the Pharmacokinetics and Safety of Bimekizumab in Children and… UCB Biopharma SRL Active, Not Recruiting 2026-07-31
NCT06959225 Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With… Incyte Corporation Active, Not Recruiting 2026-07-28
NCT06958211 Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With… Incyte Corporation Active, Not Recruiting 2026-07-08
NCT07007637 A Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Subcutaneous… MoonLake Immunotherapeutics AG Enrolling by Invitation 2026-06-08
NCT06768671 An Open-label, Single-arm Study to Evaluate Pharmacokinetics and Safety of Subcutaneous… MoonLake Immunotherapeutics AG Active, Not Recruiting 2026-05-06
Phase 2/3
NCT07287644 A Study Evaluating BFB759 in Moderate to Severe Hidradenitis Suppurativa Bluefin Biomedicine, Inc. Recruiting 2026-05-29
Phase 2
NCT07170917 Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa Sanofi Recruiting 2026-08-20
NCT07547813 A Proof-of-Concept Study of LAD328 in Adults With Hidradenitis Suppurativa Almirall, S.A. Recruiting 2026-08-17
NCT07213973 Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With… Incyte Corporation Recruiting 2026-08-06
NCT07384975 A Study to Assess NAV-240 in Adult Participants With Hidradenitis Suppurativa Navigator Medicines, Inc. Recruiting 2026-07-22
NCT07228390 A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long… Pfizer Recruiting 2026-07-09
NCT07263230 The Safety and Efficacy of Roflumilast Foam in HS Beth Israel Deaconess Medical Center Recruiting 2026-07-09
NCT07225569 A Study to Investigate Efficacy and Safety With SAR445399 in Adult Participants With… Sanofi Recruiting 2026-07-01
NCT06993233 A Study With CIT-013 in HS Patients Citryll BV Recruiting 2026-05-22

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