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Evaluation of MTHFR Gene Polymorphism and Periodontal Clinical Parameters in Healthy, Hypertensive, and Periodontitis Individuals

StatusCompleted
PhaseNot specified
Started
View on ClinicalTrials.gov ↗

Record History

  1. Minor Study First Submitted
This observational study aims to evaluate the relationship between MTHFR gene polymorphisms and periodontal clinical findings in healthy individuals, individuals with hypertension, individuals with periodontitis, and individuals with both hypertension and periodontitis. A total of 200 participants will be included in four groups of 50 participants each. Periodontal clinical measurements, including plaque index, gingival index, bleeding on probing, probing depth, and clinical attachment level, will be recorded. Venous blood samples will be collected for DNA isolation and analysis of MTHFR gene polymorphisms. The study will investigate whether MTHFR gene polymorphisms are associated with periodontal clinical parameters and hypertension.
Trial Details
NCT Number NCT07873385
Lead Sponsor Akdeniz University
Conditions
(from sponsor)
Hypertension, Periodontitis
Related terms Hypertension, Periodontal Diseases, Periodontitis
Enrollment 200 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov