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MINTER Trial: Metal Intervention aNd ThErapy With Radiotherapy In Thoracic Cancer Using Copper Donor Therapy: A Phase 2, Open-Label Study

Name: MINTER Trial: Metal Intervention aNd ThErapy With Radiotherapy In Thoracic Cancer Using Copper Donor Therapy: A Phase 2, Open-Label Study — clinical trial record (NCT07843537)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusNot Yet Recruiting

PhasePhase 2

SponsorM.D. Anderson Cancer Center

Started2027-03-01

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M.D. Anderson Cancer Center

1,223 trials monitored

See 78 trials at risk

This study is being done to test whether adding two drugs-disulfiram and copper gluconate-to radiation therapy can help overcome this resistance and improve treatment outcomes. When disulfiram is combined with copper, it forms a substance that may increase stress within cancer cells and lead to a specific type of cancer cell death knowns as "cuproptosis".

Trial Details

NCT Number	NCT07843537
Lead Sponsor	M.D. Anderson Cancer Center
Conditions	Thoracic Cancer
Enrollment	30 participants
Start Date	2027-03-01
Primary Completion	2030-03-30 (estimated)
Study Completion	2032-03-30 (estimated)
Updated on ClinicalTrials.gov	2026-09-28