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Multimodalomics-based Construction of Spatiotemporal Characteristics of Dynamic Liver Cancer Microenvironment to Characterize the Clinical Application of Immune Mechanisms in Liver Cancer

StatusRecruiting
PhaseNot specified
Started2024-10-01
View on ClinicalTrials.gov ↗
Tongji Hospital
197 trials monitored
See 2 trials at risk
Liver Cancer
1,505 trials monitored
See 60 trials at risk
This study aims to explore whether adding an additional MRI sequence to routine liver scans can better characterize the immune microenvironment of liver cancer. We plan to prospectively enroll patients diagnosed with or suspected of having liver cancer who undergo routine MRI examinations. In addition to the standard MRI protocol, participants will receive one extra MRI sequence. We will analyze the imaging features from this additional sequence and combine them with clinical data to construct a multi-omics model. The goal is to identify imaging biomarkers that can reflect the dynamic changes of the tumor microenvironment, which may help improve the diagnosis and clinical management of liver cancer.
Trial Details
NCT Number NCT07838415
Lead Sponsor Tongji Hospital
Conditions Hepatocellular Carcinoma (HCC), Treatment Response
Enrollment 400 participants
Start Date 2024-10-01
Primary Completion 2027-06 (estimated)
Study Completion 2028-06 (estimated)
Updated on ClinicalTrials.gov 2026-09-24