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Protein-Matched ADC or PDC Umbrella Trial in Advanced Pancreatic and Breast Cancer

Name: Protein-Matched ADC or PDC Umbrella Trial in Advanced Pancreatic and Breast Cancer — clinical trial record (NCT07825753)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: PROBE

StatusNot Yet Recruiting

PhasePhase 2

SponsorFudan University

Started2026-09-10

View on ClinicalTrials.gov ↗

Fudan University

624 trials monitored

See 9 trials at risk

Breast Cancer

5,180 trials monitored

See 256 trials at risk

Pancreatic Cancer

1,634 trials monitored

See 90 trials at risk

To evaluate the clinical efficacy (objective response rate, ORR) of mass spectrometry-based absolute quantification-guided selection and matching of ADC/PDC therapy in patients with locally advanced or metastatic pancreatic cancer/breast cancer, and to explore a quantitative threshold-based stratification strategy for identifying a "hidden benefit population

Trial Details

NCT Number	NCT07825753
Lead Sponsor	Fudan University
Conditions	Advanced or Metastatic Pancreatic Adenocarcinoma, Advanced or Metastatic Breast Cancer (BC)
Enrollment	225 participants
Start Date	2026-09-10
Primary Completion	2027-09-01 (estimated)
Study Completion	2030-02-01 (estimated)
Updated on ClinicalTrials.gov	2026-09-17