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Local Ablation Plus Systemic Therapy for Metachronous Liver and/or Lung Oligometastases From Nasopharyngeal Carcinoma

Name: Local Ablation Plus Systemic Therapy for Metachronous Liver and/or Lung Oligometastases From Nasopharyngeal Carcinoma — clinical trial record (NCT07824856)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusNot Yet Recruiting

PhasePhase 2

SponsorSun Yat-sen University

Started2026-10

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Sun Yat-sen University

609 trials monitored

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Head & Neck Cancer

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This single-center, open-label, randomized phase II trial evaluates whether CT-guided local ablation of liver and/or lung oligometastases, added to systemic therapy, improves the objective response rate compared with systemic therapy alone in patients with metachronous liver and/or lung oligometastases (no more than 5 lesions, each 3 cm or smaller) from nasopharyngeal carcinoma.

Trial Details

NCT Number	NCT07824856
Lead Sponsor	Sun Yat-sen University
Conditions	Nasopharyngeal Carcinoma, Neoplasm Metastasis, Lung Metastases, Liver Metastases, Oligometastatic Disease, Ablation Techniques
Enrollment	138 participants
Start Date	2026-10
Primary Completion	2028-08 (estimated)
Study Completion	2029-02 (estimated)
Updated on ClinicalTrials.gov	2026-09-17