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Greater Occipital Nerve Blockade in Veterans With Post-concussion Headache: Sub-study 2

StatusRecruiting
PhasePhase 2
Started2026-09-01
View on ClinicalTrials.gov ↗

Amendment history

2026-09-09
notable
Phase changed: Phase 1/2 → Phase 2
Interventions modified
487 trials monitored
See 35 trials at risk
Anesthetic greater occipital nerve (GON) blockade is a simple, inexpensive, and safe procedure that has demonstrable headache pain suppressing effects. In this study, Veterans with post-traumatic headache will be randomized to receive 0.0%, 0.05%, or 0.5% bupivacaine in bilateral GON blocks and the lasting (i.e., transitional) effects on headache frequency measured in a headache diary.
Trial Details
NCT Number NCT07796074
Lead Sponsor Yale University
Collaborators: VA Connecticut Healthcare System, National Headache Foundation
Conditions Post-Traumatic Headache
Enrollment 36 participants
Start Date 2026-09-01
Primary Completion 2027-09-30 (estimated)
Study Completion 2027-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-09-08