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NCT07786428 · ClinicalTrials.gov record · last posted 2026-08-26

Tailored Neoadjuvant Chemoimmunotherapy for Stage I TNBC

Name: Tailored Neoadjuvant Chemoimmunotherapy for Stage I TNBC — clinical trial record (NCT07786428)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: DETENTE-1

StatusNot Yet Recruiting

PhasePhase 2

SponsorUniversity of Texas Southwestern Medical Center

Started2026-10-01

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from the ClinicalTrials.gov record

The goal of this clinical trial is to compare the effectiveness of several treatment regimens for stage I triple negative breast cancer before surgery. The main question it aims to answer is if these regimens will reduce or completely remove all cancer cells before surgery.

Trial Details

NCT Number	NCT07786428
Lead Sponsor	University of Texas Southwestern Medical Center
Conditions	Triple-Negative Breast Cancer (TNBC)
Enrollment	60 participants
Start Date	2026-10-01
Primary Completion	2029-10-31 (estimated)
Study Completion	2030-10-31 (estimated)
Updated on ClinicalTrials.gov	2026-08-26