Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT07785102 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Single Day of Ultra-accelerated TMS With a Single Dose of NRX-101

Name: Single Day of Ultra-accelerated TMS With a Single Dose of NRX-101 — clinical trial record (NCT07785102)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: SPARC-LI

StatusNot Yet Recruiting

PhaseEarly Phase 1

SponsorMclean Hospital

Started2026-09-01

View on ClinicalTrials.gov ↗

Mclean Hospital

53 trials monitored

See 1 trial at risk

Depression

2,976 trials monitored

See 162 trials at risk

In this pilot study, investigators aim to combine D-cycloserine, lurasidone, and single-day repeated intermittent Theta Burst Stimulation (iTBS) to preliminarily assess clinical improvement in an open-label cohort and monitor for adverse events over a 6-week follow-up period.

Trial Details

NCT Number	NCT07785102
Lead Sponsor	Mclean Hospital
Conditions	Major Depression
Enrollment	30 participants
Start Date	2026-09-01
Primary Completion	2026-12-31 (estimated)
Study Completion	2027-03-31 (estimated)
Updated on ClinicalTrials.gov	2026-09-22