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Effect of GLP-1 Receptor Agonists on Periodontal Health and Response to Nonsurgical Periodontal Therapy

Study acronym: GLP1-PERIO
StatusNot Yet Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

  1. Study Status, Sponsor/Collaborators, Arms and Interventions, Eligibilityv2
  2. Study First Submitted
Cukurova University
80 trials monitored
See 1 trial at risk
Obesity
3,874 trials monitored
See 152 trials at risk
This study aims to evaluate the effects of glucagon-like peptide-1 receptor agonist (GLP-1 RA) use on periodontal health and the response to non-surgical periodontal therapy in individuals with obesity and periodontitis. Participants with obesity and periodontitis will be divided into two groups: those who have been using a GLP-1 RA for at least 3 months and those who are not using any medication for obesity. All participants will receive the same non-surgical periodontal treatment, including oral hygiene instruction, scaling, and root planing. Periodontal clinical measurements and gingival crevicular fluid samples will be collected before treatment and at 3 and 6 months after treatment. The study will compare changes in periodontal health and inflammatory markers between the two groups to determine whether GLP-1 RA use is associated with periodontal health and the response to non-surgical periodontal therapy.
Trial Details
NCT Number NCT07770906
Lead Sponsor Cukurova University
Conditions
(from sponsor)		 Periodontal Disease, Obesity & Overweight
Related terms Obesity, Overweight, Periodontal Diseases
Enrollment 40 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov