Clinical Trial

Outcomes After Planned Discontinuation of AntiSeizure Medication

Study acronym: STOP-ASM
Recruiting Phase 4
View on ClinicalTrials.gov →
Summary
The main purpose of this study is to understand the effects of continuing versus discontinuing antiseizure medications after a period of seizure-freedom. Physician guidelines endorse that after a period of seizure-freedom, the risk of another seizure may be low enough to allow patients to consider coming off antiseizure medication to see if they still need it. However, evidence is limited regarding how much continuing antiseizure medication still reduces seizures versus increases side effects after a patient has been treated for a while. This study will determine whether discontinuing antiseizure medications benefits patients.
Trial Details
NCT Number NCT07750496
Lead Sponsor University of Michigan
Collaborators: National Institute on Aging (NIA)
Conditions Epilepsy
Enrollment 40 participants
Start Date 2026-08
Primary Completion 2029-08 (estimated)
Study Completion 2029-08 (estimated)
Updated on ClinicalTrials.gov 2026-08-06