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A First-in-Human Study Investigating BG-85738 Alone or in Combination With Other Antitumor Agents in Patients With Advanced or Metastatic Solid Tumors With Rat Sarcoma Virus (RAS) Mutations

StatusRecruiting
PhasePhase 1
Started2026-09-02
View on ClinicalTrials.gov ↗

Amendment history

2026-09-09
Study Status, Contacts/Locations v1
Recruitment opened
Start dateestimated 2026-09-04→confirmed 2026-09-02
Study sites0→2
2026-07-30
Original filing
The purpose of this study is to test if the BG-85738 is safe and if it works in patients with advanced solid tumors with RAS mutations when it is given on its own and in combination.
Trial Details
NCT Number NCT07746141
Lead Sponsor BeOne Medicines
Conditions RAS Mutation, Advanced Solid Tumor, Metastatic Solid Tumor
Enrollment 100 participants
Start Date 2026-09-02
Primary Completion 2028-09-30 (estimated)
Study Completion 2028-09-30 (estimated)
Updated on ClinicalTrials.gov 2026-09-11