Managing Depressive Symptoms in ADPKD

The purpose of this research is to evaluate the feasibility and effectiveness of Digital Neurotherapy (DNT) or Capacity Coaching (CC) for managing symptoms of depression and self reported pain in Autosomal Dominant Polycystic Kidney Disease (ADPKD) compared to education alone.

NCT Number	NCT07745920
Lead Sponsor	Mayo Clinic
Conditions	Autosomal Dominant Polycystic Kidney Disease
Enrollment	105 participants
Start Date	2026-06-12
Primary Completion	2027-07-12 (estimated)
Study Completion	2027-07-12 (estimated)
Updated on ClinicalTrials.gov	2026-08-07