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Bariatric Surgery Combined With GLP-1RA: A Multicenter Study.

Name: Bariatric Surgery Combined With GLP-1RA: A Multicenter Study. — clinical trial record (NCT07732738)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: BS-GLP

StatusRecruiting

PhaseNot applicable

SponsorChina-Japan Friendship Hospital

Started2025-01-01

View on ClinicalTrials.gov ↗

China-Japan Friendship Hospital

97 trials monitored

See 2 trials at risk

Obesity

3,523 trials monitored

See 133 trials at risk

Obese patients exhibit considerable heterogeneity and complex comorbidities, making long-term effective management challenging with single therapies. While bariatric surgery remains the most effective weight-loss intervention, postoperative weight regain and metabolic deterioration require attention. GLP-1 RAs offer distinct advantages for weight and metabolic improvement, and their combined application with surgery may yield synergistic benefits. Given the lack of multi-regional validation in China's diverse population, this multicenter study aims to confirm the real-world effectiveness and generalizability of bariatric surgery plus GLP-1RA across distinct regional cohorts.

Trial Details

NCT Number	NCT07732738
Lead Sponsor	China-Japan Friendship Hospital
Conditions	Obesity
Enrollment	400 participants
Start Date	2025-01-01
Primary Completion	2027-12-30 (estimated)
Study Completion	2027-12-30 (estimated)
Updated on ClinicalTrials.gov	2026-07-29