SONATA LIFU for OCD

The study tests ATTN201, an investigational non-invasive headband that delivers low-intensity focused ultrasound (LIFU) to the subthalamic nucleus (STN) as a treatment for obsessive-compulsive disorder (OCD). It's a randomized, double-blind, 1:1 (active: sham) study with 40 total participants spanning 12-16 weeks and 14 in-person and remote visits.

NCT Number	NCT07728994
Lead Sponsor	University of Pennsylvania Collaborators: Attune Neurosciences Inc
Conditions	Obsessive Compulsive Disorder
Enrollment	40 participants
Start Date	2026-07-01
Primary Completion	2028-07-31 (estimated)
Study Completion	2028-10-31 (estimated)
Updated on ClinicalTrials.gov	2026-07-27