Clinical Trial

Transventricular Off-pump Mitral Valve Repair

Study acronym: TRANSOM
Recruiting
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Summary
The purpose of this study is to assess the safety and effectiveness (usefulness) of an investigational technique used to repair the mitral valve for patients with mitral regurgitation due to a defective valve leaflet. This procedure is called trans-ventricular off-pump mitral valve repair (TRANSOM) and it repairs the mitral valve by replacing some of the cords that support the mitral valve. This type of repair is minimally-invasive since it is performed through a small incision and avoids making a breast-bone-splitting incision.
Trial Details
NCT Number NCT07726173
Lead Sponsor Johns Hopkins University
Conditions Mitral Valve (MV) Regurgitation
Enrollment 175 participants
Start Date 2026-06-08
Primary Completion 2027-07-01 (estimated)
Study Completion 2029-07-01 (estimated)
Updated on ClinicalTrials.gov 2026-07-24