Clinical Trial

A Single and Multiple Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP6590 in Participants With Normal Weight, Overweight and Obesity

Recruiting Early Phase 1
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to learn about the safety and tolerability of drug ZP6590 and to learn how the body processes the drug ZP6590 in adults. The main questions it aims to answer are: * Is the drug ZP6590 safe and well tolerated when administered as escalating single and multiple doses of the ZP6590? * How quickly and to what extent the administered investigational drug is absorbed and distributed, and how long it takes to be eliminated from the body? In the first Part of the study: Participants will: • Get a single ascending dose of the drug ZP6590 or placebo and will have an observation period of 4 weeks. In the second Part of the study: Participants will: • Get multiple dosages of the drug ZP6590 or placebo for 6 or 12 weeks followed by an observation period of 6 weeks after last dosing.
Trial Details
NCT Number NCT07721597
Lead Sponsor Zealand Pharma
Conditions Healthy Participants Study, Overweight and Obese Adults, First in Man Study to Evaluate Initial Safety
Enrollment 88 participants
Start Date 2026-07-09
Primary Completion 2027-09-06 (estimated)
Study Completion 2027-09-06 (estimated)
Updated on ClinicalTrials.gov 2026-08-13