AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight

The purpose of this clinical study is to find out if zenagamtide is safe and effective for treating people who have excess body weight. There are 2 study treatments in this study taken as oral tablets once a day. Participants will either get zenagamtide (the treatment being tested) or Placebo (treatment that has no active medicine in it). Which treatment participants get is decided by chance.

NCT Number	NCT07720271
Lead Sponsor	Novo Nordisk A/S
Conditions	Overweight, Obesity
Enrollment	950 participants
Start Date	2026-09-01
Primary Completion	2028-06-27 (estimated)
Study Completion	2028-08-22 (estimated)
Updated on ClinicalTrials.gov	2026-07-22