Clinical Trial

Magnetic Resonance Imaging Assessment of Multiorgan Health in Obesity

Study acronym: FIT-YOUNG
Recruiting
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Summary
The goal of this study is to quantify the body composition and organ fat distribution changes with obesity interventions in adolescents with severe obesity. The main question the investigators aim to answer is if there is improvement in organ health with weight loss intervention. The investigators will be comparing the degree of these changes between children being treated with GLP1 receptor agonists in addition to lifestyle changes and those managed with lifestyle changes alone. Participants will undergo MRI body composition at baseline and after 9 months.
Trial Details
NCT Number NCT07702825
Lead Sponsor Alder Hey Children's NHS Foundation Trust
Conditions Childhood Obesity
Enrollment 30 participants
Start Date 2026-03-06
Primary Completion 2027-12 (estimated)
Study Completion 2028-01 (estimated)
Updated on ClinicalTrials.gov 2026-07-14