Clinical Trial

A Study of Trastuzumab Deruxtecan (T-DXd) and Cetuximab in People With Colorectal Cancer

Not Yet Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The purpose of this study is find out whether the combination of trastuzumab deruxtecan (T-DXd) and cetuximab is an effective treatment for participants with metastatic and/or unresectable colorectal cancer that expresses low levels of HER2 and that has gotten worse after receiving standard treatment.
Trial Details
NCT Number NCT07691489
Lead Sponsor Memorial Sloan Kettering Cancer Center
Collaborators: AstraZeneca, Eli Lilly and Company, National Institutes of Health (NIH)
Conditions Colorectal Cancer, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum
Enrollment 27 participants
Start Date 2026-08
Primary Completion 2029-06 (estimated)
Study Completion 2029-06 (estimated)
Updated on ClinicalTrials.gov 2026-07-09