Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT): Open Label

Smell dysfunction significantly impacts quality of life and safety, with limited effective treatments. This open-label study evaluates the preliminary efficacy of combining non-invasive trigeminal nerve stimulation (TNS) with standard smell training (ST) to improve olfactory function. Participants will complete 8 weeks of at-home treatment and attend three in-person visits for assessment. Improvements in smell, mood, sleep, and quality of life will be measured.

NCT Number	NCT07689773
Lead Sponsor	Medical University of South Carolina
Conditions	Olfactory Impairment
Enrollment	60 participants
Start Date	2026-07-10
Primary Completion	2028-06-30 (estimated)
Study Completion	2028-06-30 (estimated)
Updated on ClinicalTrials.gov	2026-08-12