Clinical Trial

Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training

Study acronym: CIPOD
Recruiting
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Summary
A research study to assess the baseline olfactory function, mental health status, clinical severity, and immunological profile in patients with smell loss. The impact of a 3-month olfactory training program on smell function, immunological changes, and mental health in patients with smell loss will be evaluated. The primary purpose of this study is to investigate tissue and blood samples to identify molecules that may be related to smell loss, ultimately aiming to develop future treatments for this condition and correlate with cognition.
Trial Details
NCT Number NCT07681973
Lead Sponsor The Cleveland Clinic
Conditions Smell Loss, Chronic Rhinosinusitis (CRS)
Enrollment 52 participants
Start Date 2025-12-09
Primary Completion 2026-12-31 (estimated)
Study Completion 2027-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-07-02