Clinical Trial

Individualized Primary Clinical Target Volume Based on Margin Expansion for Nasopharyngeal Carcinoma

Study acronym: CTV-MARGIN-NPC
Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
This is a non-inferiority, multicenter, randomized phase 3 trial aimed at investigating the impact of individualized primary clinical target volume based on margin expansion on patients' prognosis and complications compared with the consensus primary clinical target volume based on margin expansion and stepwise extension pattern for patients with newly diagnosed non-metastatic nasopharyngeal carcinoma.
Protocol Amendment History 3 changes
critical Recruitment opened 2026-07-29
notable Primary completion pushed: 2029-06-30 -> 2029-07-30 2026-07-29
minor Completion pushed: 2034-06-30 -> 2034-07-30 2026-07-29
Trial Details
NCT Number NCT07661771
Lead Sponsor Sun Yat-sen University
Conditions Non-metastatic Nasopharyngeal Carcinoma
Enrollment 568 participants
Start Date 2026-07-24
Primary Completion 2029-07-30 (estimated)
Study Completion 2034-07-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-28