Clinical Trial

Topical Calcipotriol Versus Photodynamic Therapy in the Treatment of Oral Leukoplakia

Active, Not Recruiting Phase 2/3
View on ClinicalTrials.gov →
Record status
This record was last updated June 22, 2026 (before its estimated August 10, 2026 completion). Its status may not reflect the trial's current state.
Summary
The goal of this clinical trial is to learn if calcipotriol and photodynamic therapy are equally effective in treatment of leukoplakia or not. The main questions it aims to answer are: do lesions decrease or disappear when treated by calcipotriol or PDT? does the drug affect the salivary biomarkers Participants will: Take calcipotriol daily for 4 weeks or perform 4 PDT sessions over 4 weeks measure changes in salivary biomarkers be followed up for 3 months
Trial Details
NCT Number NCT07658508
Lead Sponsor Alexandria University
Conditions Oral Leukoplakia
Enrollment 30 participants
Start Date 2025-07-16
Primary Completion 2026-08-10 (estimated)
Study Completion 2026-09-10 (estimated)
Updated on ClinicalTrials.gov 2026-06-22