Clinical Trial

Infant RSV Immunity Study

Study acronym: IRIS
Recruiting
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Summary
Respiratory Syncytial Virus (RSV) is a main global cause of respiratory illness and death in infants. Previous infant vaccine trials have failed to demonstrate protection. Moreover, RSV infection during early infancy, particularly in infants younger than 4 months of age, is associated with more severe disease, reduced immune protection, and an increased risk of developing childhood asthma. This study aim to investigate the immunological and long-term health effects of a first exposure to RSV early (\<4 months) versus late (\>6-9 months) in infancy.
Trial Details
NCT Number NCT07653347
Lead Sponsor University of British Columbia
Conditions Respiratory Synctial Virus, Asthma Childhood
Enrollment 300 participants
Start Date 2026-01-15
Primary Completion 2027-06-01 (estimated)
Study Completion 2029-12-01 (estimated)
Updated on ClinicalTrials.gov 2026-06-17